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Note 5 - Acquisition of EGEN, Inc. (Tables)
12 Months Ended
Dec. 31, 2017
Notes Tables  
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
Property and equipment, net
  $
35,000
 
In-process research and development
   
24,211,000
 
Other Intangible assets (Covenant not to compete)
   
1,591,000
 
Goodwill
   
1,976,000
 
Total assets:
   
27,813,000
 
Accounts payable and accrued liabilities
   
(235,000
)
Net assets acquired
  $
27,578,000
 
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
   
Year Ended
December 31,
 
2018
  $
227,316
 
2019
   
227,316
 
2020
   
227,316
 
2021
   
113,660
 
Total
  $
795,608