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Note 7 - Other Accrued Liabilities
12 Months Ended
Dec. 31, 2017
Notes to Financial Statements  
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
7.
OTHER ACCRUED LIABILITIES
 
 
Other accrued liabilities at
December 31,
201
7
and
2016
include the following:
 
 
   
Year Ended December 31,
 
   
201
7
   
201
6
 
Amounts due to contract research organizations and
other contractual agreements
  $
665,373
    $
1,115,193
 
Accrued payroll and related benefits
   
1,258,265
     
1,066,751
 
Accrued professional fees
   
264,668
     
259,550
 
Accrued interest on notes payable
   
-
     
22,241
 
Other
   
94,521
     
20,021
 
Total
  $
2,282,827
    $
2,483,756