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Condensed Consolidated Statements of Operations (Unaudited) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Licensing revenue $ 125,000 $ 125,000 $ 375,000 $ 375,000
Operating expenses:        
Research and development 3,348,847 4,225,132 9,870,754 11,002,675
General and administrative 1,174,250 1,496,471 4,291,482 4,888,301
Total operating expenses 4,523,097 5,721,603 14,162,236 15,890,976
Loss from operations (4,398,097) (5,596,603) (13,787,236) (15,515,976)
Other income (expense):        
Gain (loss) from change in valuation of earn-out milestone liability 1,246,151 (662,410) 670,172 (556,382)
Loss from impairment of in-process research and development (2,520,000) (2,520,000)
Investment income, net 524 8,133 3,941 21,832
Interest expense (161,025) (91,756) (608,576)
Other income 93 2,218 3,545 1,965
Total other expense, net (1,273,232) (813,084) (1,934,098) (1,141,161)
Net loss (5,671,329) (6,409,687) (15,721,334) (16,657,137)
Deemed dividend related to warrant modification (345,685)
Net loss attributable to common shareholders $ (5,671,329) $ (6,409,687) $ (16,067,019) $ (16,657,137)
Net loss per common share        
Basic and diluted (in dollars per share) $ (0.70) $ (3.22) $ (3.04) $ (9.27)
Weighted average shares outstanding        
Basic and diluted (in shares) 8,054,658 1,993,233 5,171,699 1,796,184