Note 11 - Earn-out Milestone Liability (Tables)

6 Months Ended

Jun. 30, 2017

Notes Tables

Schedule of Changes in Earn out Milestone Liabilities [Table Text Block]

Balance at January 1, 2017	$	13,188,226
Non-cash charge from the adjustment for the change in fair value included in net loss		575,979
Balance at June 30, 2017	$	13,764,205

Schedule of Milestone Risk Adjustment Assessment [Table Text Block]

Date	Risk-adjustment Assessment of each Milestone				Discount  Rate		Estimated Time to Achieve (years)
June 30, 2017		50%	to	80%		9%		1.50	to	2.00
March 31, 2017		50%	to	80%		9%		1.75	to	2.25
December 31, 2016		50%	to	80%		9%		2.00	to	2.50
June 30, 2016		10%	to	75%		9%		0.50	to	2.00
March 31, 2016		10%	to	75%		9%		0.25	to	2.25
December 31, 2015		10%	to	75%		9%		0.50	to	2.50