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Note 7 - Accrued Liabilities
6 Months Ended
Jun. 30, 2017
Notes to Financial Statements  
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Note
7.
Accrued Liabilities
 
Other accrued liabilities at
June 30, 2017
and
December 31, 2016
include the following:
 
 
 
June 30, 2017
 
 
December 31, 2016
 
Amounts due to contract research organizations and other contractual agreements
  $
804,762
    $
1,115,193
 
Accrued payroll and related benefits
   
1,841,208
     
1,066,751
 
Accrued professional fees
   
245,900
     
259,550
 
Accrued interest on notes payable
   
     
22,241
 
Other
   
20,021
     
20,021
 
Total
  $
2,911,891
    $
2,483,756