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Note 13 - Warrants - Summary of Warrant Activity (Details) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Warrants outstanding (in shares) 5,894,675 5,069,815
Warrants outstanding (in dollars per share) $ 6.37 $ 8.18
Warrants issued in connection with the May 2015 equity transaction (in shares) 16,066,371 1,950,000
Warrants issued in connection with the May 2015 equity transaction (in dollars per share) $ 0.92 $ 2.60
Warrants expired during 2015 (in shares) (879,163) (1,125,140)
Warrants expired during 2015 (in dollars per share) $ 14.94 $ 7.98
Warrants outstanding (in shares) 20,831,883 5,894,675
Warrants outstanding (in dollars per share) $ 1.88 $ 6.37
Warrants exercised during 2016 (in shares) (250,000)  
Warrants exercised during 2016 (in dollars per share) $ 0.01  
Aggregate intrinsic value of outstanding warrants $ 534,000  
Weighted average remaining contractual terms (Year) [1] 3 years 116 days  
[1] Does not include the remaining Pre-Funded Warrants issued in the June 2016 Offering (totaling 1,850,000 shares underlying these warrants) as these warrants have no expiration date.