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Note 9 - Accrued Liabilities
3 Months Ended
Mar. 31, 2016
Notes to Financial Statements  
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Note 9. Accrued Liabilities
 
Other accrued liabilities at March 31, 2016 and December 31, 2015 include the following:
 
 
 
March 31, 2016
 
 
December 31,
201
5
 
Amounts due to contract research organizations and
other contractual agreements
  $ 852,243     $ 571,615  
Accrued payroll and related benefits
    760,341       947,078  
Accrued professional fees
    411,600       319,200  
Accrued interest on notes payable
    53,117       62,136  
Other
    19,740       19,740  
Total
  $ 2,097,041     $ 1,919,769