Note 19 - Selected Quarterly Financial Data (Unaudited) (Details) - Selected Quarterly Financial Data - USD ($)	3 Months Ended							6 Months Ended	12 Months Ended
	Dec. 31, 2015	Sep. 30, 2015	Mar. 31, 2015	Dec. 31, 2014	Sep. 30, 2014	Jun. 30, 2014	Mar. 31, 2014	Sep. 30, 2015	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
2015
Total revenue	$ 125,000	$ 125,000	$ 125,000	$ 125,000	$ 125,000	$ 125,000	$ 125,000	$ 125,000
Net loss	$ (5,514,000)	$ (4,267,000)	$ (7,005,000)	$ (6,455,000)	$ (6,942,000)	$ (6,673,000)	$ (5,423,000)	$ (5,675,000)	$ (22,461,084)	$ (25,494,273)	$ (8,251,358)
Basic and diluted net loss per share (in Dollars per share)	$ (0.24)	$ (0.19)	$ (0.35)	$ (0.32)	$ (0.35)	$ (0.38)	$ (0.33)	$ (0.27)