Note 13 - Warrants (Details) - Summary of Warrant Activity - $ / shares	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Note 13 - Warrants (Details) - Summary of Warrant Activity [Line Items]
Warrants outstanding	5,069,815	3,170,520	1,747,478
Warrants outstanding	$ 8.18	$ 10.65	$ 15.17
Weighted average remaining contractual terms (years)	2 years 146 days
Warrant Issued	1,950,000	1,801,802	1,341,382
Warrant Issued	$ 2.60	$ 4.10	$ 5.31
Warrants expired during 2015	(1,125,140)
Warrants expired during 2015	$ 7.98
Warrants exercised for common stock in 2013			(15,833)
Warrants exercised for common stock in 2013			$ 14.63
Warrants outstanding	5,894,675	5,069,815	3,170,520
Warrants outstanding	$ 6.37	$ 8.18	$ 10.65
Hercules Warrant [Member]
Note 13 - Warrants (Details) - Summary of Warrant Activity [Line Items]
Warrant Issued		97,493	97,493
Warrant Issued		$ 3.59	$ 3.59