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Note 4 - Fair Value of Financial Instruments (Tables)
12 Months Ended
Dec. 31, 2014
Fair Value Disclosures [Abstract]  
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
   

Total Fair

Value on

the

Balance

Sheet

   

Quoted

Prices

In Active

Markets

For

Identical

Assets

/Liabilities

(Level 1)

   

Significant

Other

Observable

Inputs

(Level 2)

   

Significant

Unobservable

Inputs

(Level 3)

 

Assets:

                               

Recurring items as of December 31, 2014

                               

Short-term investments available for sale

  $ 24,173,406     $ 24,173,406          

 
                                 

Non-recurring items as of December 31, 2014

                               

In-process research and development (Note 5)

  $ 25,801,728    

   

    $ 25,801,728  
                                 

Goodwill (Note 5)

  $ 1,976,101    

   

    $ 1,976,101  
                                 

Recurring items as of December 31, 2013

                               

Short-term investments available for sale

  $ 37,156,381     $ 37,156,381    

   

 
                                 

Liabilities:

                               

Recurring items as of December 31, 2014

                               

Common stock warrant liability (Note 13)

  $ 275,008    

   

    $ 275,008  
                                 

Earn-out milestone liability (Note 12)

  $ 13,663,710    

   

    $ 13,663,710  
                                 

As of December 31, 2013

                               

Common stock warrant liability (Note 13)

  $ 3,026    

   

    $ 3,026