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Condensed Consolidated Balance Sheets (Current Period Unaudited) (USD $)
Jun. 30, 2014
Dec. 31, 2013
Current assets:    
Cash and cash equivalents $ 9,597,408 $ 5,718,504
Investment securities – available for sale, at fair value 40,171,059 37,156,381
Accrued interest receivable on investment securities 291,147 212,048
Advances, deposits and other current assets 486,144 675,186
Total current assets 50,545,758 43,762,119
Property and equipment (at cost, less accumulated depreciation of $1,435,190 and $1,264,190, respectively) 850,995 832,886
Other assets:    
Finite lived intangible assets, net 25,801,728  
Total other assets 28,181,275 1,075,567
Goodwill 1,938,814  
Deposits, deferred fees and other assets 423,858 1,054,942
Total assets 79,578,028 45,670,572
Current liabilities:    
Accounts payable 3,616,864 1,452,436
Accrued liabilities 1,873,120 2,707,653
Notes payable – current portion 1,776,603 10,891
Deferred revenue – current portion 500,000 500,000
Total current liabilities 7,766,587 4,670,980
Earnout milestone liability 13,877,659  
Common stock warrant liability 494,874 3,026
Notes payable, net of discounts 7,868,197 5,000,000
Deferred revenue 3,750,000 4,000,000
Other non-current liabilities 461,449 472,731
Total liabilities 34,218,766 14,146,737
Stockholders' equity:    
Preferred stock, $0.01 par value: 100,000 shares authorized; no shares issued or outstanding at June 30, 2014 and December 31, 2013, respectively 0 0
Common stock, $0.01 par value; 75,000,000 shares authorized; 20,082,353 and 13,737,970 shares issued at June 30, 2014 and December 31, 2013, and 19,958,121 and 13,604,975 shares outstanding at June 30, 2014 and December 31, 2013, respectively 200,824 137,380
Additional paid-in capital 228,944,110 203,139,142
Accumulated other comprehensive loss (11,829) (44,166)
Accumulated deficit (181,512,022) (169,287,157)
Subtotal 47,621,083 33,945,199
Treasury stock, at cost (124,232 and 132,995 shares at June 30, 2014 and December 31, 2013, respectively) (2,261,821) (2,421,364)
Total stockholders' equity 45,359,262 31,523,835
Total liabilities and stockholders' equity 79,578,028 45,670,572
In Process Research and Development [Member]
   
Other assets:    
Finite lived intangible assets, net 25,801,728  
Patents [Member]
   
Other assets:    
Finite lived intangible assets, net $ 16,875 $ 20,625