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Statements of Cash Flows (USD $)
3 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Cash flows from operating activities:    
Net loss $ (5,422,693) $ (650,974)
Non-cash items included in net loss:    
Depreciation and amortization 87,375 76,875
Change in fair value of common stock warrant liability (3,026) (4,280,297)
Deferred revenue (125,000) (125,000)
Stock-based compensation 607,230 263,192
Treasury shares issued for services and 401(k) matching contribution 9,323 20,835
Change in deferred rent liability (5,186) (3,829)
Deferred finance charges 89,675 31,560
Net changes in:    
Deposits, advances, other current assets and other assets (229,200) (225,660)
Accounts payable 649,577 1,841,037
Accrued liabilities (501,815) (157,534)
Cash received for non-refundable research and development fee   5,000,000
Net cash (used in) provided by operating activities: (4,843,740) 1,790,205
Cash flows from investing activities:    
Purchases of investment securities (17,862,837) (20,245,204)
Proceeds from sale and maturity of investment securities 7,780,000 3,048,000
Net cash used in investing activities (10,082,837) (17,197,204)
Cash flows from financing activities:    
Proceeds from sale of common stock equity, net of issuance costs 13,825,231 6,711,173
Proceeds from sale of preferred stock, net of issuance costs   13,648,663
Proceeds from exercise of options to purchase common stock   174,871
Principal payments on notes payable (10,891) (14,461)
Net cash provided by financing activities 13,814,340 20,782,190
Decrease in cash and cash equivalents (1,112,237) (5,375,191)
Cash and cash equivalents at beginning of period 5,718,504 14,991,488
Cash and cash equivalents at end of period 4,606,267 20,366,679
Supplemental disclosures of cash flow information:    
Interest paid 141,038 180,928
Common Stock Warrants (Member)
   
Cash flows from financing activities:    
Proceeds from exercise of common stock warrants   $ 261,944