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Statements of Cash Flows (Unaudited) (USD $)
6 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Cash flows from operating activities:    
Net loss $ (230,090) $ (12,290,626)
Depreciation and amortization 153,750 107,910
Change in fair value of common stock warrant liability (8,660,417) 369,723
Deferred revenue (250,000)  
Stock-based compensation 734,673 557,021
Treasury shares issued for services and 401(k) matching contribution 20,837 81,617
Change in deferred rent liability (8,563) 62,914
Deferred finance charges 62,823  
Cash received for non-refundable research and development fee 5,000,000  
Net changes in:    
Accrued interest on short term investments and other current assets (166,666) 45,662
Accounts payable (817,058) 295,457
Accrued liabilities 572,880 (141,522)
Net cash used in operating activities: (3,587,831) (10,911,844)
Cash flows from investing activities:    
Purchases of investment securities (39,804,383) (11,366,148)
Proceeds from sale and maturity of investment securities 5,048,000 9,440,882
Refund of deposit for letter of credit 50,000  
Purchases of property and equipment (57,494) (371,215)
Net cash used in investing activities (34,763,877) (2,296,481)
Cash flows from financing activities:    
Proceeds from sale of preferred stock, net of issuance costs 13,616,442  
Proceeds from sale of common stock equity, net of issuance costs 15,640,213  
Proceeds from exercise of common stock warrants 200,000  
Proceeds from exercise of options to purchase common stock 181,337 200,000
Proceeds from note payable   4,853,137
Principal payments on notes payable (319,188) (82,556)
Net cash provided by financing activities 29,380,748 4,770,581
Decrease in cash and cash equivalents (8,970,960) (8,437,744)
Cash and cash equivalents at beginning of period 14,991,488 20,145,854
Cash and cash equivalents at end of period 6,020,528 11,708,110
Supplemental disclosures of cash flow information:    
Interest paid 247,899 16,275
Common Stock Warrants (Member)
   
Cash flows from financing activities:    
Proceeds from exercise of common stock warrants $ 261,944