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Statements of Cash Flows (Unaudited) (USD $)
3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Cash flows from operating activities:    
Net loss $ (650,974) $ (6,186,241)
Non-cash items included in net income (loss):    
Depreciation and amortization 76,875 53,955
Change in fair value of common stock warrant liability (4,280,297) (77,600)
Deferred revenue 4,875,000  
Stock-based compensation 263,192 305,127
Treasury shares issued for services and 401(k) matching contribution 20,835 50,384
Change in deferred rent liability (3,829) 65,467
Net changes in:    
Accrued interest on short term investments and other current assets (194,100) (216,934)
Accounts payable 1,841,037 (301,358)
Accrued liabilities (157,534) 579,323
Net cash provided by (used in) operating activities: 1,790,205 (5,727,877)
Cash flows from investing activities:    
Purchases of investment securities (20,245,204) (10,309,461)
Proceeds from sale and maturity of investment securities 3,048,000 5,237,504
Purchases of property and equipment   (177,600)
Net cash used in investing activities (17,197,204) (5,249,557)
Cash flows from financing activities:    
Proceeds from sale of Preferred Stock, net of issuance costs 13,648,663  
Proceeds from sale of common stock equity, net of issuance costs 6,711,173  
Proceeds from exercise of common stock warrants 200,000  
Proceeds from exercise of options to purchase common stock 174,871  
Principal payments on notes payable (14,461) (46,341)
Net cash provided by (used in) financing activities 20,782,190 (46,341)
Increase (decrease) in cash and cash equivalents 5,375,191 (11,023,775)
Cash and cash equivalents at beginning of period 14,991,488 20,145,854
Cash and cash equivalents at end of period 20,366,679 9,122,079
Supplemental disclosures of cash flow information:    
Interest paid 180,928 5,701
Common Stock Warrants (Member)
   
Cash flows from financing activities:    
Proceeds from exercise of common stock warrants $ 261,944