Statement of Changes in Stockholders' Equity (Deficiency) (USD $)	1 Months Ended	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Balance	$ 11,961,858	$ 11,961,858	$ 26,193,568	$ (4,575,525)	$ 10,035,794
Net loss	(26,568,382)	(26,568,382)	(23,222,678)	(18,818,435)
Unrealized loss on investments available for sale	150,093	150,093	(258,333)	(86,540)
Stock-based compensation expense	1,143,764	1,100,000	1,207,886	1,653,060
Issuance of restricted stock upon vesting	697,220
Shares issued in exchange for services				18,060
Comprehensive loss:
Issuance of Common Stock Out of Treasury	107,049		131,910
Registered Direct and Private Placement Private Placement common stock offerings (in Shares)	37,302,785	37,302,785	33,186,325
Restricted Stock [Member] | Common Stock [Member]
Issuance of restricted stock upon vesting				863
Issuance of restricted stock upon vesting (in Shares)				86,277
Restricted Stock [Member] | Additional Paid-in Capital [Member]
Issuance of restricted stock upon vesting				(863)
Direct and Private Placement [Member] | Common Stock [Member]
Comprehensive loss:
Registered Direct and Private Placement Private Placement common stock offerings			161,294
Registered Direct and Private Placement Private Placement common stock offerings (in Shares)			16,129,373
Direct and Private Placement [Member] | Additional Paid-in Capital [Member]
Comprehensive loss:
Registered Direct and Private Placement Private Placement common stock offerings			44,543,243
Direct and Private Placement [Member]
Comprehensive loss:
Registered Direct and Private Placement Private Placement common stock offerings			44,704,537
Series A Redeemable, Convertible Preferred Stock (Member) | Additional Paid-in Capital [Member]
Comprehensive loss:
Valuation of Common Stock Warrants			2,030,000
Series A Redeemable, Convertible Preferred Stock (Member)
Comprehensive loss:
Valuation of Common Stock Warrants			2,030,000
In Connection with Note Payable (Member) | Additional Paid-in Capital [Member]
Comprehensive loss:
Valuation of Common Stock Warrants	73,654
In Connection with Note Payable (Member)
Comprehensive loss:
Valuation of Common Stock Warrants	73,654
Common Stock [Member] | Shares Issued under CEFF, net of issuance costs (Member)
Shares issued under CEFF, net of issuance costs			13,405	11,039
Shares issued under CEFF, net of issuance costs (in Shares)			1,340,514	1,103,919
Common Stock [Member] | Series A Preferred Stock [Member]
Comprehensive loss:
Convertible Securities			20,833
Convertible Securities (in Shares)			2,083,322
Common Stock [Member]
Balance	379,677	379,677	338,991	140,914	128,952
Balance (in Shares)	37,302,785	37,302,785	33,186,325	13,331,096	12,134,900
Issuance of restricted stock upon vesting	2,638		976
Issuance of restricted stock upon vesting (in Shares)	263,783		97,612
Shares issued in exchange for services				60
Shares issued in exchange for services (in Shares)				6,000
Comprehensive loss:
Convertible Securities	38,048		1,569
Convertible Securities (in Shares)	3,804,868		156,866
Issuance of Common Stock Out of Treasury (in Shares)	47,809		47,542
Additional Paid-in Capital [Member] | Shares Issued under CEFF, net of issuance costs (Member)
Shares issued under CEFF, net of issuance costs			3,102,682	2,611,497
Additional Paid-in Capital [Member] | Series A Preferred Stock [Member]
Comprehensive loss:
Convertible Securities			2,610,514
Additional Paid-in Capital [Member]
Balance	165,276,069	165,276,069	153,237,225	99,316,859	95,035,165
Stock-based compensation expense	1,143,764		1,207,886	1,653,060
Issuance of restricted stock upon vesting	694,582		(976)
Shares issued in exchange for services				18,000
Comprehensive loss:
Convertible Securities	10,126,844		426,768
Issuance of Common Stock Out of Treasury			249
Treasury Stock [Member]
Balance	(2,690,511)	(2,690,511)	(2,884,125)	(3,076,670)	(3,076,670)
Balance (in Shares)	664,923	664,923	712,732	760,274	760,274
Comprehensive loss:
Issuance of Common Stock Out of Treasury	193,614		98,176
Issuance of Common Stock Out of Treasury (in Shares)	(47,809)		(24,241)
Accumulated Other Comprehensive Income (Loss) [Member]
Balance	(126,607)	(126,607)	(276,700)	(18,367)	68,173
Unrealized loss on investments available for sale	150,093	150,093	(258,333)	(86,540)
Retained Earnings [Member]
Balance	(150,876,770)	(150,876,770)	(124,221,823)	(100,938,261)	(82,119,826)
Net loss	(26,568,382)		(23,222,678)	(18,818,435)
Comprehensive loss:
Issuance of Common Stock Out of Treasury	(86,565)		(48,366)
Warrant [Member]
Comprehensive loss:
Convertible Securities	10,164,892		428,337
Shares Issued under CEFF, net of issuance costs (Member)
Shares issued under CEFF, net of issuance costs			3,116,087	2,622,536
Series A Preferred Stock [Member]
Comprehensive loss:
Convertible Securities			$ 2,631,347