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Statements of Operations (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Licensing revenue   $ 2,000,000  
Operating expenses:      
Research and development 15,770,166 19,863,836 14,714,460
General and administrative 6,372,551 5,154,933 4,922,967
Total operating expenses 22,142,717 25,018,769 19,637,427
Loss from operations (22,142,717) (23,018,769) (19,637,427)
Other (expense) income:      
(Loss) gain from valuation of common stock warrant liability (4,117,534) 81,733 573,760
Investment income 52,322 174,064 32,289
Interest expense (359,413) (501,855) (31,517)
Other (expense) income (1,040) 42,149 244,460
Total other (expense) income (4,425,665) (203,909) 818,992
Net loss $ (26,568,382) $ (23,222,678) $ (18,818,435)
Net loss per common share – basic and diluted (in Dollars per share) $ (0.76) $ (1.11) $ (1.52)
Weighted average common shares outstanding – basic and diluted (in Shares) 34,789,068 20,917,678 12,375,402