Exhibit 32.1

CELSION CORPORATION

CERTIFICATION

PURSUANT TO 18 UNITED STATES CODE § 1350

The undersigned hereby certifies that the Quarterly Report on Form 10-Q for the period ended March 31, 2008 of Celsion Corporation (the “Company”) filed with the Securities and Exchange Commission on the date hereof fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended, and that the information contained in such report fairly presents, in all material respects, the financial condition and results of operations of the Company.

May 12, 2009
	/s/ Michael H. Tardugno
	Michael H. Tardugno
	Chief Executive Officer
May 12, 2009
	/s/ Sean Moran
	Sean Moran
	Senior Vice President & Chief Financial Officer