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    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0000745463</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000005301</seriesId>
        <classId>C000014481</classId>
        <classId>C000080481</classId>
        <classId>C000014479</classId>
        <classId>C000077400</classId>
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    </filerInfo>
  </headerData>
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    <genInfo>
      <regName>Eaton Vance Mutual Funds Trust</regName>
      <regFileNumber>811-04015</regFileNumber>
      <regCik>0000745463</regCik>
      <regLei>549300C67AFHZKODE756</regLei>
      <regStreet1>One Post Office Square</regStreet1>
      <regCity>Boston</regCity>
      <regStateConditional regCountry="US" regState="US-MA"/>
      <regZipOrPostalCode>02109</regZipOrPostalCode>
      <regPhone>617-482-8260</regPhone>
      <seriesName>Eaton Vance Strategic Income Fund</seriesName>
      <seriesId>S000005301</seriesId>
      <seriesLei>TRR43XJWNSQTT4ZJ4373</seriesLei>
      <repPdEnd>2025-10-31</repPdEnd>
      <repPdDate>2025-04-30</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>9308482806.26</totAssets>
      <totLiabs>1566815.50</totLiabs>
      <netAssets>9306915990.76</netAssets>
      <assetsAttrMiscSec>0.00000000</assetsAttrMiscSec>
      <assetsInvested>0.00000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.00000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.00000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.00000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.00000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.00000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.00000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.00000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.00000000</amtPayAftOneYrOther>
      <delayDeliv>0.00000000</delayDeliv>
      <standByCommit>0.00000000</standByCommit>
      <liquidPref>0.00000000</liquidPref>
      <cshNotRptdInCorD>4349.15000000</cshNotRptdInCorD>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
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          <monthlyTotReturn classId="C000080481" rtn1="1.45000000" rtn2="0.10000000" rtn3="0.55000000"/>
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          <monthlyTotReturn classId="C000077400" rtn1="1.65000000" rtn2="0.14000000" rtn3="0.59000000"/>
        </monthlyTotReturns>
        <othMon1 netRealizedGain="0.00000000" netUnrealizedAppr="843501.68000000"/>
        <othMon2 netRealizedGain="0.00000000" netUnrealizedAppr="-3962356.33000000"/>
        <othMon3 netRealizedGain="0.00000000" netUnrealizedAppr="-5388774.40000000"/>
      </returnInfo>
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      <mon2Flow redemption="171338698.28000000" reinvestment="48733048.72000000" sales="675659519.05000000"/>
      <mon3Flow redemption="321354656.68000000" reinvestment="51684185.10000000" sales="752113613.48000000"/>

      <varInfo>

        <fundsDesignatedInfo>
          <nameDesignatedIndex>Securities Portfolio</nameDesignatedIndex>
          <indexIdentifier>Securities Portfolio</indexIdentifier>

        </fundsDesignatedInfo>

      </varInfo>
    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>Emerging Markets Local Income Portfolio</name>
        <lei>TJHVIYYZOASBZ463H550</lei>
        <title>Emerging Markets Local Income Portfolio</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="FR7A_MASTER"/>
        </identifiers>
        <balance>35146435.16000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>131799131.84000000</valUSD>
        <pctVal>1.416141845170</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>N/A</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Global Macro Absolute Return Advantage Portfolio</name>
        <lei>NKY7JRBKJHQQ68KJ6252</lei>
        <title>Global Macro Absolute Return Advantage Portfolio</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="FS8A_MASTER"/>
        </identifiers>
        <balance>145580220.64000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1585368602.82000000</valUSD>
        <pctVal>17.03430657796</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>N/A</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Global Opportunities Portfolio</name>
        <lei>732CSYB5YI2A4VM2EI15</lei>
        <title>Global Opportunities Portfolio</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="FV2C_MASTER"/>
        </identifiers>
        <balance>334329666.58000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6449219268.29000000</valUSD>
        <pctVal>69.29491224260</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>N/A</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Eaton Vance Emerging Markets Debt Opportunities Fund</name>
        <lei>549300RCSLWCTPOHZZ51</lei>
        <title>Eaton Vance Emerging Markets Debt Opportunities Fund</title>
        <cusip>27827V105</cusip>
        <identifiers>
          <isin value="US27827V1052"/>
        </identifiers>
        <balance>49306761.21000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>389523413.52000000</valUSD>
        <pctVal>4.185311373893</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Senior Debt Portfolio (MA)</name>
        <lei>5493009DZ4DLQ0NAB757</lei>
        <title>Senior Debt Portfolio (MA)</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="FS3A_MASTER"/>
        </identifiers>
        <balance>49102168.54000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>352553570.15000000</valUSD>
        <pctVal>3.788081578258</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>N/A</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HIGH INCOME OPPORTUNITIES PORTFOLIO</name>
        <lei>Q9J0C6S550YJ63X9DD38</lei>
        <title>HIGH INCOME OPPORTUNITIES PORTFOLIO</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="FR8A_MASTER"/>
        </identifiers>
        <balance>41452347.42000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>400015152.57000000</valUSD>
        <pctVal>4.298041939640</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>N/A</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>

      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2025-05-21</ncom:dateSigned>
      <ncom:nameOfApplicant>Eaton Vance Mutual Funds Trust</ncom:nameOfApplicant>
      <ncom:signature>James Kirchner</ncom:signature>
      <ncom:signerName>James Kirchner</ncom:signerName>
      <ncom:title>Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
