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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOW - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash flows from operating activities:    
Net loss $ (53,796) $ (32,808)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 867 775
Amortization and premium of marketable securities, net (2,267) (3,313)
Loss on sale or disposal of assets 4 8
Stock-based compensation expense 9,316 7,202
Changes in operating assets and liabilities:    
Accounts and other receivables (364) (43)
Prepaid and other current assets 1,852 (6,209)
Other assets (662)  
Accounts payable and accrued expenses (8,718) (4,781)
Other liabilities (604) (1,469)
Net cash used in operating activities (54,372) (40,638)
Cash flows from investing activities:    
Sales and maturities of marketable securities 195,037 77,311
Purchases of marketable securities (151,822) (392,178)
Acquisition of property and equipment (265) (344)
Net cash provided by (used in) investing activities 42,950 (315,211)
Cash flows from financing activities:    
Net proceeds from stock issuances   432,298
Proceeds from issuance of stock from employee benefit plans 202 3,814
Net cash provided by financing activities 202 436,112
Net (decrease) increase in cash and cash equivalents (11,220) 80,263
Cash and cash equivalents at beginning of period 28,356 34,814
Cash and cash equivalents at end of period 17,136 115,077
Non-cash investing activities    
Accrued construction in progress $ 504 $ 105