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Stock-Based Compensation - Stock Option Activity (Details) - Employee Stock Option - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2025
Dec. 31, 2024
Shares    
Options outstanding at beginning of the period 7,540,109  
Granted 40,400  
Exercised (380)  
Canceled (81,381)  
Options outstanding at the end of the period 7,498,748 7,540,109
Options vested and expected to vest at the end of the period 7,400,964  
Options exercisable at the end of the period 4,233,279  
Shares available for grant under the Celldex Therapeutics, Inc. 2021 Omnibus Equity Incentive Plan (as amended, effective as of June 13, 2024) at March 31, 2025 2,413,314  
Weighted Average Exercise Price Per Share    
Options outstanding at beginning of the period $ 31.47  
Granted 22.04  
Exercised 8.38  
Canceled 39.24  
Options outstanding at the end of the period 31.34 $ 31.47
Options vested and expected to Vest at the end of the period 31.29  
Options exercisable at the end of the period $ 29.14  
Weighted Average Remaining Contractual Term (In Years)    
Options outstanding at the beginning of the period 7 years 2 months 12 days 7 years 6 months
Options vested and expected to vest at the end of the period 7 years 2 months 12 days  
Options exercisable at the end of the period 6 years 1 month 6 days