Segment Information - Research and development expenses disaggregated by nature (Details) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2025	Mar. 31, 2024
Segment Information
Total R&D expense	$ 52,614	$ 31,661
Single reportable segment
Segment Information
Personnel	13,600	11,440
Laboratory supplies	2,168	1,308
Facility	1,406	1,286
Product development	32,166	15,525
Other expenses	3,274	2,102
Total R&D expense	$ 52,614	$ 31,661

Facility expense fees incurred during the period.

No definition available.

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- Definition

Product development expenses including but not limited to clinical investigator site fees, external trial monitoring costs, data accumulation costs, contracted research and outside clinical drug product manufacturing.

+ References

No definition available.

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- Definition

Amount of expense for salary, wage, profit sharing; incentive and equity-based compensation; and other employee benefit.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 220
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03(4))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147483621/220-10-S99-2

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- Definition

Amount of other research and development expense.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 730
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482916/730-10-50-1

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- Definition

Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 280
-SubTopic 10
-Name Accounting Standards Codification
-Section 55
-Paragraph 48
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482785/280-10-55-48

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 985
-SubTopic 20
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Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 730
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Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 912
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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

Amount of expense associated with supplies that were used during the current accounting period.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 942
-SubTopic 220
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.9-04(14))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478524/942-220-S99-1

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