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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Cash flows from operating activities:    
Net loss $ (78,685) $ (53,796)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 854 867
Amortization and premium of marketable securities, net (630) (2,267)
Loss on sale or disposal of assets 3 4
Stock-based compensation expense 8,523 9,316
Changes in operating assets and liabilities:    
Accounts and other receivables 1,785 (364)
Prepaid and other current assets 6,283 1,852
Other assets (2,076) (662)
Accounts payable and accrued expenses (287) (8,718)
Other liabilities (1,358) (604)
Net cash used in operating activities (65,588) (54,372)
Cash flows from investing activities:    
Sales and maturities of marketable securities 133,366 195,037
Purchases of marketable securities (59,608) (151,822)
Acquisition of property and equipment (1,639) (265)
Net cash provided by investing activities 72,119 42,950
Cash flows from financing activities:    
Proceeds from issuance of stock from employee benefit plans 327 202
Net cash provided by financing activities 327 202
Net increase (decrease) in cash and cash equivalents 6,858 (11,220)
Cash and cash equivalents at beginning of period 28,871 28,356
Cash and cash equivalents at end of period 35,729 17,136
Non-cash investing activities    
Accrued construction in progress $ 953 $ 504