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Income Taxes - Reconciliation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Reconciliation between the amount of reported income tax and the amount computed using U.S. Statutory rate (in amount)      
Pre-tax loss $ (258,757) $ (157,863) $ (141,429)
Loss at statutory rates (54,339) (33,151) (29,700)
Research and development credits (11,809) (7,332) (5,237)
State taxes   (15,375) (13,691)
Stock Compensation 14,704    
Other 2,178    
Expiration of Federal and State NOLs and R&D credits   82,825 15,141
Other Adjustments 294 662 (1,130)
Change in valuation allowance 48,972 (27,629) 34,617
Income tax (benefit) provision $ 0 $ 0 $ 0
Reconciliation between the amount of reported income tax and the amount computed using the U.S. statutory rate (in percentage)      
Loss at statutory rates 21.00%    
Research and development credits 4.60%    
Tax Effect 0.00%    
Stock Compensation (5.70%)    
Other (0.90%)    
Other Adjustments (0.10%)    
Change in valuation allowance (18.90%)    
Income tax (benefit) provision 0.00%