Property and Equipment, Net (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Property and Equipment
Total property and equipment	$ 29,238	$ 27,810
Less: accumulated depreciation and amortization	(23,904)	(23,464)
Property and equipment, net	5,334	4,346
Depreciation and amortization expense	3,380	3,177	$ 3,008
Laboratory equipment
Property and Equipment
Total property and equipment	10,657	10,411
Manufacturing equipment
Property and Equipment
Total property and equipment	2,587	3,010
Office furniture and equipment
Property and Equipment
Total property and equipment	3,932	3,965
Leasehold improvements
Property and Equipment
Total property and equipment	10,338	10,285
Construction in progress
Property and Equipment
Total property and equipment	1,724	139
Property and equipment
Property and Equipment
Depreciation and amortization expense	$ 1,800	$ 1,600	$ 1,500