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Nature of Business and Overview (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Nature of Business and Overview      
Cash, cash equivalents and marketable securities $ 518,600    
Net loss 258,757 $ 157,863 $ 141,429
Net cash used in operations $ 210,945 $ 157,778 $ 107,291