X0202 3 2005-12-23 0 0000743884 MACROCHEM CORP MCMP.OB 0001225978 SCO CAPITAL PARTNERS LLC 1285 AVENUE OF THE AMERICAS 35TH FLOOR NEW YORK NY 10019 0 0 1 0 0001294343 Rouhandeh Steven H C/O SCO CAPITAL PARTNERS LLC 1285 AVENUE OF THE AMERICAS, 35TH FLOOR NEW YORK NY 10019 0 0 1 0 Series C Cumulative Convertible Preferred Stock .175 Common Stock 11428571 D Common Stock Purchase Warrants .21 2005-12-23 2011-12-23 Common Stock 11428571 D Placement Agent Warrants .175 2005-12-23 2011-12-23 Common Stock 1428571 I By SCO Securities LLC Amounts reflect adjustment for the 1 for 7 reverse stock split effected by the issuer on December 30, 2005. This Form 3 is being filed by Steven H. Rouhandeh individually and by SCO Capital Partners LLC, an entity of which Mr. Rouhandeh is the sole member. SCO Capital Partners LLC is the direct beneficial owner of these securities. These securities are convertible at any time and have no expiration date. Mr. Rouhandeh is the sole member of the entity that is the sole member of SCO Securities LLC. SCO Capital Partners LLC 2006-01-03 Steven H. Rouhandeh 2006-01-03