UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM N-Q

QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED
MANAGEMENT INVESTMENT COMPANIES

Investment Company Act file number 811- 3999

John Hancock Investment Trust II
(Exact name of registrant as specified in charter)

601 Congress Street, Boston, Massachusetts 02210
(Address of principal executive offices) (Zip code)

Alfred E. Ouellette, Senior Attorney & Assistant Secretary

601 Congress Street

Boston, Massachusetts 02210
(Name and address of agent for service)

Registrant's telephone number, including area code: 617-663-4324

Date of fiscal year end:	October 31
Date of reporting period:	January 31, 2006

ITEM 1. SCHEDULE OF INVESTMENTS

John Hancock
Regional Bank Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

Issuer	Shares	Value
Common stocks 99.46%		$2,070,271,555
(Cost $686,604,594)
Asset Management & Custody Banks 8.65%		179,821,011
Bank of New York Co., Inc. (The) (NY)	1,868,898	59,449,645
Mellon Financial Corp. (PA)	1,466,554	51,725,360
Northern Trust Corp. (IL)	252,500	13,183,025
State Street Corp. (MA)	917,350	55,462,981
Consumer Finance 0.44%		9,199,652
Capital One Financial Corp. (VA)	110,440	9,199,652
Diversified Banks 12.99%		270,481,444
Bank of America Corp. (NC)	1,305,941	57,761,770
Comerica, Inc. (MI)	165,697	9,191,213
Toronto-Dominion Bank (The) (Canada)	388,310	20,634,793
U.S. Bancorp. (MN)	1,979,987	59,221,411
Wachovia Corp. (NC)	1,160,977	63,656,369
Wells Fargo & Co. (CA)	962,410	60,015,888
Other Diversified Financial Services 4.89%		101,816,900
Citigroup, Inc. (NY)	1,047,290	48,782,768
JPMorgan Chase & Co. (NY)	1,334,192	53,034,132
Regional Banks 66.01%		1,374,083,518
Alabama National Bancorp. (AL)	129,600	9,009,792
AmSouth Bancorp. (AL)	1,131,910	31,252,035
BB&T Corp. (NC)	1,026,432	40,071,905
BOK Financial Corp. (OK)	123,500	5,631,600
Bryn Mawr Bank Corp. (PA)	337,800	7,151,226
Cardinal Financial Corp. (VA)	248,800	2,928,376
Cascade Bancorp. (OR)	30,604	795,704
Chittenden Corp. (VT)	1,094,357	31,046,908
City Holding Co. (WV)	112,756	4,201,289
City National Corp. (CA)	535,800	40,168,926
CoBiz, Inc. (CO)	127,750	2,351,877
Colonial BancGroup, Inc. (The) (AL)	735,100	18,303,990
Columbia Bancorp. (OR)	38,775	814,663
Columbia Banking System, Inc. (WA)	65,680	2,118,180
Commerce Bancshares, Inc. (MO)	999,245	50,511,835

Page 1

John Hancock
Regional Bank Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

Commercial Bankshares, Inc. (FL)	284,456	10,613,053
Community Bancorp. (NV) (I)	28,330	883,613
Compass Bancshares, Inc. (AL)	1,240,125	60,418,890
Cullen/Frost Bankers, Inc. (TX)	1,125,450	60,481,683
Dearborn Bancorp., Inc. (MI) (I)	168,689	4,068,779
Eurobancshares, Inc. (Puerto Rico) (I)	238,170	3,374,869
F.N.B. Corp. (PA)	290,257	4,887,928
Fifth Third Bancorp. (OH)	1,333,727	50,108,123
First Horizon National Corp. (TN)	1,314,800	49,791,476
First Midwest Bancorp., Inc. (IL)	134,000	4,677,940
First Republic Bank (CA)	260,614	9,892,907
FirstMerit Corp. (OH)	8,550	215,887
Fulton Financial Corp. (PA)	1,253,080	22,492,786
Glacier Bancorp., Inc. (MT)	19,000	603,820
Greene County Bancshares, Inc. (TN)	53,000	1,496,720
Hancock Holding Co. (MS)	475,094	19,478,854
Hudson United Bancorp. (NJ)	398,759	16,608,312
Independent Bank Corp. (MA)	735,000	21,675,150
Independent Bank Corp. (MI)	279,300	7,714,266
KeyCorp (OH)	723,934	25,620,024
Lakeland Financial Corp. (IN)	18,000	794,880
M&T Bank Corp. (NY)	554,153	60,014,770
Marshall & Ilsley Corp. (WI)	1,405,689	58,954,597
MB Financial, Inc. (IL)	323,650	11,350,405
Mercantile Bankshares Corp. (MD)	1,377,075	52,259,996
Midwest Banc Holdings, Inc. (IL)	35,650	847,401
National City Corp. (OH)	1,665,212	56,916,946
North Fork Bancorp., Inc. (NY)	2,215,831	56,991,173
Oriental Financial Group, Inc. (Puerto Rico)	56,765	781,654
Placer Sierra Bancshares (CA)	39,450	1,050,948
PNC Financial Services Group, Inc. (PA)	859,900	55,773,114
Prosperity Bancshares, Inc. (TX)	104,000	3,029,520
Provident Bankshares Corp. (MD)	164,389	6,038,008
Regions Financial Corp. (AL)	388,100	12,877,158
Republic Bancorp., Inc. (MI)	150,040	1,943,018
Sandy Spring Bancorp., Inc. (MD)	3,100	108,221
Seacoast Banking Corp. of Florida (FL)	548,790	13,873,411
Sky Financial Group, Inc. (OH)	261,000	6,712,920
SNB Bancshares, Inc. (TX) (I)	255,660	4,448,484
Southcoast Financial Corp. (SC) (I)	99,100	2,462,635
South Financial Group, Inc. (The) (SC)	49,700	1,296,176
Southwest Bancorp., Inc. (OK)	13,250	295,342
State National Bancshares, Inc. (TX) (I)	28,420	774,161
Sterling Bancshares, Inc. (TX)	434,145	7,271,929
SunTrust Banks, Inc. (GA)	836,337	59,756,279
Susquehanna Bancshares, Inc. (PA)	508,693	12,279,849
Taylor Capital Group, Inc. (IL)	121,250	4,699,650

Page 2

John Hancock
Regional Bank Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

TCF Financial Corp. (MN)		2,227,484	55,664,825
TD Banknorth, Inc. (ME)		1,041,114	30,171,484
Texas Regional Bancshares, Inc. (Class A) (TX)		827,125	25,458,908
Texas United Bancshares, Inc. (TX)		127,900	2,367,429
TriCo Bancshares (CA)		655,150	15,907,042
Trustmark Corp. (MS)		167,000	4,729,440
UnionBanCal Corp. (CA)		259,800	17,429,982
Virginia Commerce Bancorp., Inc. (VA) (I)		45,827	1,480,670
Virginia Financial Group, Inc. (VA)		55,629	2,225,160
Westamerica Bancorp. (CA)		433,075	23,308,097
Western Alliance Bancorp. (NV) (I)		52,620	1,662,792
Whitney Holding Corp. (LA)		547,730	18,020,317
Zions Bancorp. (UT)		766,300	60,591,341
Thrifts & Mortgage Finance 6.48%			134,869,030
Astoria Financial Corp. (NY)		528,050	15,207,840
BankUnited Financial Corp., (Class A) (FL)		70,350	1,976,835
Countrywide Financial Corp. (CA)		272,998	9,129,053
Hudson City Bancorp., Inc. (NJ)		940,490	11,680,886
MAF Bancorp., Inc. (IL)		301,743	12,971,932
New York Community Bancorp., Inc. (NY)		125,000	2,132,500
Sovereign Bancorp., Inc. (PA)		80,000	1,744,000
Washington Federal, Inc. (WA)		1,126,098	27,184,006
Washington Mutual, Inc. (WA)		1,204,111	50,957,978
Webster Financial Corp. (CT)		40,000	1,884,000
	Interest	Par value
Issuer, description, maturity date	rate (%)	($000)	Value
Short-term investments 0.54%			$11,250,000
(Cost $11,250,000)
Joint Repurchase Agreement 0.54%			11,250,000
Investment in a joint repurchase agreement transaction with
Morgan Stanley - Dated 01-31-06 due 02-01-06 (Secured
by U.S. Treasury Inflation Indexed Note 3.375% due 01-15-12
and 1.625% due 01-15-15)	4.390	11,250	11,250,000
Total investments 100.00%			$2,081,521,555

Page 3

John Hancock
Regional Bank Fund
Footnotes to Schedule of Investments
January 31, 2006 (unaudited)

(I) Non-income-producing security.

Parenthetical disclosure of a foreign country in the security description represents country of a foreign issuer.

The percentage shown for each investment category is the total value of that category as a percentage of the total investments of the Fund.

The cost of investments owned on January 31, 2006, including short-term investments, was $697,854,594. Gross unrealized appreciation and depreciation of investments aggregated $1,385,157,960 and $1,490,999, respectively, resulting in net unrealized appreciation of $1,383,666,961.

Footnotes to Schedule of Investments - Page 1

John Hancock
Small Cap Equity Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

Issuer	Shares	Value
Common stocks 95.44%		$452,970,014
(Cost $336,515,567)
Aerospace & Defense 1.30%		6,183,765
Argon ST, Inc. (I)	215,989	6,183,765
Biotechnology 1.06%		5,040,000
Martek Biosciences Corp. (I)	175,000	5,040,000
Broadcasting & Cable TV 0.78%		3,691,380
XM Satellite Radio Holdings, Inc. (Class A) (I)	141,000	3,691,380
Building Products 2.43%		11,518,107
Modtech Holdings, Inc. (I)	599,318	4,770,571
Simpson Manufacturing Co., Inc. (I)	174,400	6,747,536
Casinos & Gaming 2.44%		11,585,000
Alliance Gaming Corp. (I)	350,000	5,323,500
Mikohn Gaming Corp. (I)	450,000	3,379,500
Pinnacle Entertainment, Inc. (I)	100,000	2,882,000
Communications Equipment 0.92%		4,368,000
SeaChange International, Inc. (I)	525,000	4,368,000
Computer Hardware 4.23%		20,069,067
Stratasys, Inc. (I)	320,550	8,315,067
Trident Microsystems, Inc. (I)	450,000	11,754,000
Construction & Engineering 0.19%		884,677
Stantec, Inc. (Canada) (I)	9,000	336,690
Stantec, Inc. (Canada) (E)(I)	14,700	547,987
Construction & Farm Machinery & Heavy Trucks 3.37%		15,998,000
Joy Global, Inc. (U)	130,700	7,063,028
Oshkosh Truck Corp.	181,200	8,934,972
Construction Materials 2.00%		9,487,500
Headwaters, Inc. (I)	275,000	9,487,500

Page 1

John Hancock
Small Cap Equity Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

Consumer Finance 1.38%		6,558,600
Infinity Property & Casualty Corp.	170,000	6,558,600
Diversified Chemicals 0.76%		3,613,400
American Vanguard Corp.	140,000	3,613,400
Diversified Commercial Services 2.86%		13,557,750
Quixote Corp.	225,000	4,785,750
Universal Technical Institute, Inc. (I)	240,000	8,772,000
Diversified Financial Services 5.08%		24,126,750
Asset Acceptance Capital Corp. (I)	205,000	5,002,000
Euronet Worldwide, Inc. (I)	425,000	13,714,750
FTI Consulting, Inc. (I)	200,000	5,410,000
Drug Retail 1.09%		5,175,540
Matrixx Initiatives, Inc. (I)	208,439	5,175,540
Electrical Components & Equipment 6.00%		28,470,039
Axsys Technologies, Inc. (I)	125,000	2,062,500
Intermagnetics General Corp. (I)	234,866	9,474,494
KFx, Inc. (I)	345,000	6,931,050
Medis Technologies Ltd. (I)(L)	551,682	10,001,995
Electronic Equipment Manufacturers 6.12%		29,034,949
Cognex Corp.	218,000	6,361,240
FARO Technologies, Inc. (I)	387,300	6,169,689
II-VI, Inc. (I)	299,800	5,216,520
Measurement Specialties, Inc. (I)	437,500	11,287,500
Electronic Manufacturing Services 0.62%		2,928,265
LoJack Corp. (I)	119,132	2,928,265
Employment Services 1.06%		5,030,280
Barrett Business Services, Inc. (I)	188,400	5,030,280
Health Care Equipment 8.21%		38,964,591
BioLase Technology, Inc. (I)	81,800	621,680
Cyberonics, Inc. (I)	185,000	5,551,850
Electro-Optical Sciences, Inc. (I)(W)	597,200	3,200,992
EPIX Pharmaceuticals, Inc. (I)	22,591	102,789
Kensey Nash Corp. (I)	191,600	4,676,956
Kyphon, Inc. (I)	107,800	4,481,246
ResMed, Inc. (I)	184,800	7,288,512

Page 2

John Hancock
Small Cap Equity Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

Somanetics Corp. (I)	180,000	4,586,400
Sonosite, Inc.	214,900	8,454,166
Health Care Services 2.64%		12,525,750
Allscripts Healthcare Solutions, Inc. (I)	375,000	6,603,750
HealthExtras, Inc. (I)	180,000	5,922,000
Health Care Supplies 2.14%		10,139,530
ev3, Inc. (I)	141,900	2,298,780
IntraLase Corp. (I)	395,000	7,840,750
Home Furnishings 1.37%		6,486,000
Select Comfort Corp. (I)	235,000	6,486,000
Homebuilding 0.72%		3,422,209
Orleans Homebuilders, Inc.	198,850	3,422,209
Industrial Machinery 2.37%		11,273,165
Middleby Corp. (The) (I)	37,000	3,496,500
Raven Industries, Inc.	246,097	7,776,665
Internet Software & Services 3.38%		16,043,800
aQuantive, Inc. (I)	140,000	3,641,400
Opsware, Inc. (I)	750,000	5,490,000
SafeNet, Inc. (I)	220,000	6,912,400
Life & Health Insurance 0.97%		4,600,296
Scottish Re Group Ltd. (Cayman Islands) (I)	186,852	4,600,296
Movies & Entertainment 1.71%		8,110,000
Imax Corp. (Canada) (I)(L)	1,000,000	8,110,000
Oil & Gas Drilling 2.27%		10,768,700
InterOil Corp. (Canada) (I)	255,000	4,717,500
TETRA Technologies, Inc. (I)	152,500	6,051,200
Oil & Gas Equipment & Services 3.00%		14,246,685
ATP Oil & Gas Corp. (I)	56,700	2,412,585
Core Laboratories N.V., (Netherlands) (I)	140,000	6,241,200
Superior Energy Services, Inc. (I)	206,000	5,592,900
Oil & Gas Exploration & Production 1.16%		5,515,700
KCS Energy, Inc. (I)	190,000	5,515,700

Page 3

John Hancock
Small Cap Equity Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

Packaged Foods & Meats 0.31%		1,458,366
Galaxy Nutritional Foods, Inc. (I)(W)	1,139,348	1,458,366
Pharmaceuticals 1.68%		7,980,400
Medicis Pharmaceutical Corp. (Class A)	160,000	4,945,600
NitroMed, Inc. (I)	270,000	3,034,800
Property & Casualty Insurance 1.13%		5,374,950
ProAssurance Corp. (I)	105,000	5,374,950
Regional Banks 5.74%		27,241,788
Boston Private Financial Holdings, Inc.	145,000	4,428,300
IBERIABANK Corp.	99,875	5,523,088
Pacific Mercantile Bancorp. (I)	300,000	5,439,000
Umpqua Holdings Corp.	230,000	6,481,400
Wintrust Financial Corp.	100,000	5,370,000
Restaurants 0.91%		4,342,800
Texas Roadhouse, Inc. (Class A) (I)	280,000	4,342,800
Semiconductor Equipment 1.88%		8,946,000
FormFactor, Inc. (I)	300,000	8,946,000
Specialty Chemicals 0.91%		4,317,300
Cabot Microelectronics Corp. (I)	130,000	4,317,300
Steel 0.11%		518,500
Allegheny Technologies, Inc. (I)(U)	10,000	518,500
Systems Software 3.52%		16,709,545
Access Integrated Technologies, Inc. (I)	341,500	4,490,725
Concur Technologies, Inc. (I)	478,500	7,904,820
Progress Software Corp. (I)	150,000	4,314,000
Technology Distributors 1.28%		6,068,570
Global Imaging Systems, Inc. (I)	130,000	4,596,800
iRobot Corp. (I)	41,400	1,471,770
Telecommunication Services 0.94%		4,461,800
Comtech Telecommunications Corp. (I)	140,000	4,461,800
Trucking 1.21%		5,735,000
Celadon Group, Inc. (I)	185,000	5,735,000

Page 4

John Hancock
Small Cap Equity Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)

Wireless Telecommunication Services 2.19%			10,397,500
Radyne ComStream, Inc. (I)		375,000	5,148,750
Spectralink Corp.		425,000	5,248,750
Issuer		Shares	Value
Warrants 0.00%			$0
(Cost $0)
Systems Software 0.00%			0
Access Integrated Technologies, Inc. (B)		75,000	0
	Interest	Par value
Issuer, description, maturity date	rate (%)	($000)	Value
Short-term investments 4.56%			$21,643,384
(Cost $21,643,384)
Joint Repurchase Agreement 2.63%			12,505,000
Investment in a joint repurchase agreement transaction with
Morgan Stanley - Dated 01-31-06 due 02-01-06 (Secured by U.S.
Treasury Inflation Indexed Note 3.375% due 01-15-12 and 1.625%
due 01-15-15)	4.390	12,505	12,505,000
		Shares
Cash Equivalents 1.93%			9,138,384
AIM Cash Investment Trust (T)		9,138,384	9,138,384
Total investments 100.00%			$474,613,398

Page 5

John Hancock
Small Cap Equity Fund
Summary of written options outstanding on
January 31, 2006 (unaudited)

	Number of	Exercise	Expiration
Name of issuer	contracts	price	date	Value
CALLS
Allegheny Technologies, Inc.	100	$45	03-20-06	$78,000
Joy Global, Inc.	146	45	02-20-06	137,240
				$215,240

Summary of written options

John Hancock
Small Cap Equity Fund
Footnotes to Schedule of Investments
January 31, 2006 (unaudited)

(B) This security is fair valued in good faith under procedures established by the Board of Trustees.

(E) Parenthetical disclosure of a foreign country in the security description represents country of local currency; par value is expressed in local currency.

(I) Non-income-producing security.

(L) All or a portion of this security is on loan as of January 31, 2006.

(T) Represents investment of securities lending collateral.

(U) All or a portion of this security is pledged as collateral for written call options. See the additional information on the outstanding written options in the table preceding these footnotes.

(W) Issuer is an affiliate of John Hancock Advisers, LLC.

Parenthetical disclosure of a foreign country in the security description represents country of a foreign issuer; however, security is U.S. dollar-denominated.

The percentage shown for each investment category is the total value of that category as a percentage of the total investments of the Fund.

The cost of investments owned on January 31, 2006, including short-term investments, was $358,158,951. Gross unrealized appreciation and depreciation of investments aggregated $137,524,092 and $21,069,645, respectively, resulting in net unrealized appreciation of $116,454,447.

Footnotes to Schedule of Investments - Page 1

John Hancock
Financial Industries Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)
Issuer	Shares	Value
Common stocks 81.25%		$923,873,474
(Cost $575,215,695)
Asset Management & Custody Banks 10.62%		120,798,759
Affiliated Managers Group, Inc. (I) (L)	128,100	11,887,680
Alliance Capital Management Holding L.P.	85,000	5,137,400
Ameriprise Financial, Inc.	90,200	3,670,238
Bank of New York Co., Inc. (The)	557,500	17,734,075
BlackRock, Inc. (Class A)	101,900	13,532,320
Franklin Resources, Inc.	136,500	13,445,250
Legg Mason, Inc.	151,650	19,669,005
State Street Corp.	590,850	35,722,791
Consumer Finance 4.14%		47,020,275
American Express Co.	577,500	30,289,875
Capital One Financial Corp. (L)	90,000	7,497,000
SLM Corp. (L)	165,000	9,233,400
Data Processing & Outsourced Services 2.54%		28,857,514
First Data Corp.	185,000	8,343,500
Fiserv, Inc. (I)	321,800	14,152,764
Paychex, Inc. (L)	175,000	6,361,250
Diversified Banks 10.82%		123,059,414
Bank of America Corp. (L)	893,355	39,513,092
U.S. Bancorp.	577,000	17,258,070
Wachovia Corp. (L)	638,605	35,014,712
Wells Fargo & Co. (L)	501,500	31,273,540
Diversified Commercial Services 0.97%		11,071,488
Wright Express Corp. (I)	435,200	11,071,488
Insurance Brokers 0.99%		11,272,978
Marsh & McLennan Cos., Inc.	268,150	8,149,078
Willis Group Holdings Ltd. (Bermuda)	90,000	3,123,900
Investment Banking & Brokerage 12.17%		138,332,650
Goldman Sachs Group, Inc. (The)	233,950	33,045,437
Lehman Brothers Holdings, Inc. (L)	222,500	31,250,125
Merrill Lynch & Co., Inc.	598,100	44,899,367

Page 1

John Hancock
Financial Industries Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)
Morgan Stanley	359,350	22,082,057
TD Ameritrade Holding Corp.	348,600	7,055,664
Life & Health Insurance 6.44%		73,277,599
AFLAC, Inc. (L)	231,800	10,883,010
Conseco, Inc. (I)	524,320	12,777,678
MetLife, Inc.	225,000	11,286,000
Prudential Financial, Inc. (L)	363,500	27,386,090
Scottish Re Group Ltd. (Cayman Islands) (L)	444,550	10,944,821
Multi-Line Insurance 7.16%		81,376,998
American International Group, Inc.	523,100	34,242,126
Assurant, Inc.	166,700	7,654,864
Genworth Financial, Inc. (Class A) (L)	641,617	21,019,373
Hartford Financial Services Group, Inc. (The)	224,500	18,460,635
Other Diversified Financial Services 6.61%		75,128,644
Citigroup, Inc.	882,000	41,083,560
JPMorgan Chase & Co.	683,000	27,149,250
National Financial Partners Corp. (L)	128,870	6,895,834
Property & Casualty Insurance 3.63%		41,274,253
ACE Ltd. (Cayman Islands)	203,000	11,114,250
Allstate Corp. (The)	266,500	13,871,325
Ambac Financial Group, Inc. (L)	115,850	8,898,438
Arch Capital Group Ltd. (Bermuda) (I)	136,000	7,390,240
Real Estate Investment Trusts 0.41%		4,668,300
Host Marriott Corp. (L)	234,000	4,668,300
Regional Banks 3.88%		44,106,717
City National Corp.	93,500	7,009,695
Fifth Third Bancorp. (L)	179,775	6,754,147
M&T Bank Corp.	145,500	15,757,650
North Fork Bancorp., Inc.	212,000	5,452,640
Zions Bancorp.	115,500	9,132,585
Reinsurance 4.65%		52,922,493
Assured Guaranty Ltd. (Bermuda)	422,960	10,772,791
Axis Capital Holdings Ltd. (Bermuda)	429,480	12,841,452
Max Re Capital Ltd. (Bermuda)	178,650	4,736,012
PartnerRe Ltd. (Bermuda)	195,500	12,077,990
Platinum Underwriters Holdings Ltd. (Bermuda)	209,550	6,422,708
RenaissanceRe Holdings Ltd. (Bermuda)	134,000	6,071,540

Page 2

John Hancock
Financial Industries Fund
Securities owned by the Fund on
January 31, 2006 (unaudited)
Specialized Finance 0.79%			9,014,460
CIT Group, Inc.		169,000	9,014,460
Thrifts & Mortgage Finance 4.85%			55,138,782
Countrywide Financial Corp. (L)		242,500	8,109,200
Freddie Mac		307,000	20,833,020
Golden West Financial Corp. (L)		136,000	9,604,320
Hudson City Bancorp., Inc.		500,980	6,222,172
Radian Group, Inc. (L)		125,000	7,153,750
Washington Mutual, Inc.		76,000	3,216,320
Trading Companies & Distributors 0.58%			6,552,150
GATX Corp.		165,000	6,552,150
	Interest	Par value
Issuer, description, maturity date	rate (%)	($000)	Value
Short-term investments 18.75%			$213,188,813
(Cost $213,188,813)
Joint Repurchase Agreement 1.90%			21,583,000
Investment in a joint repurchase agreement transaction
with Morgan Stanley - Dated 01-31-06 due 02-01-06
(Secured by U.S. Treasury Inflation Indexed Note 3.375%
due 01-15-12 and 1.625% due 01-15-15)	4.390	21,583	21,583,000
		Shares
Cash Equivalents 16.85%			191,605,813
AIM Cash Investment Trust (T)		191,605,813	191,605,813
Total investments 100.00%			$1,137,062,287

Page 3

John Hancock
Financial Industries Fund
Footnotes to Schedule of Investments
January 31, 2006 (unaudited)

(I) Non-income-producing security.

(L) All or a portion of this security is on loan as of January 31, 2006.

(T) Represents investment of securities lending collateral.

Parenthetical disclosure of a foreign country in the security description represents country of a foreign
issuer.

The percentage shown for each investment category is the total value of that category as a percentage
of the total investments of the Fund.

The cost of investments owned on January 31, 2006, including short-term investments, was $788,404,508.
Gross unrealized appreciation and depreciation of investments aggregated $349,698,543 and $1,040,764,
respectively, resulting in net unrealized appreciation of $348,657,779.

ITEM 2. CONTROLS AND PROCEDURES.

(a) Based upon their evaluation of the registrant's disclosure controls and procedures as conducted within 90 days of the filing date of this Form N-Q, the registrant's principal executive officer and principal accounting officer have concluded that those disclosure controls and procedures provide reasonable assurance that the material information required to be disclosed by the registrant on this report is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission's rules and forms.

(b) There were no changes in the registrant's internal control over financial reporting that occurred during the registrant's last fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting.

ITEM 3. EXHIBITS.

Separate certifications for the registrant's principal executive officer and principal accounting officer, as required by Rule 30a-2(a) under the Investment Company Act of 1940, are attached.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

John Hancock Investment Trust II

By: /s/ Keith F. Hartstein
-------------------------------------
Keith F. Hartstein
President and Chief Executive Officer
Date: March 24, 2006

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By: /s/ Keith F. Hartstein
-------------------------------------
Keith F. Hartstein
President and Chief Executive Officer
Date: March 24, 2006

By: /s/ John G. Vrysen
-------------------------------------
John G. Vrysen

Executive Vice President and Chief Financial Officer

Date: March 24, 2006