Exhibit 99.1

FOR IMMEDIATE RELEASE

Contact:

Jeffrey W. Farrar

Executive Vice President, COO & CFO

(434)773-2274

farrarj@amnb.com

AMERICAN NATIONAL BANKSHARES

REPORTS SECOND QUARTER EARNINGS

Danville, VA, July 21, 2022 – American National Bankshares Inc. (NASDAQ: AMNB) (“American National” or the “Company”) today reported second quarter 2022 earnings of $8.1 million, or $0.76 per diluted common share. Those results compare to earnings of $10.8 million, or $0.99 per diluted common share, during the same quarter in the prior year, and earnings of $9.0 million, or $0.84 per diluted common share, for the first quarter of 2022. Earnings for the six months ended June 30, 2022 were $17.1 million, or $1.60 per diluted common share, compared to $22.1 million, or $2.01 diluted common share, for the same period of 2021.

President and Chief Executive Officer, Jeffrey V. Haley, commented, “Core earnings remained solid during the quarter, with strong growth in net interest income reflecting our earnings capacity in a rising rate environment and offsetting some pressure on our fee based lines of business. Operating expenses remained stable, and we saw a return to a more normalized level of provision expense primarily associated with our loan growth. Asset quality remains strong and while we do not see any deterioration at this time, we are maintaining a watchful eye on a slowing economy.

“We continue to focus on adding talent and investing in the business. We successfully implemented several major projects during the quarter, including contactless debit cards and a new treasury management platform. Many other projects are in flight to further our digital offerings and better serve our customers.

“Looking forward, we should continue to benefit from rising rates in the short term, which should mitigate expected pressures on fee-based revenues and operating costs. Our history of exceptional credit quality should serve us well if we do experience an economic downturn.”

Second quarter 2022 highlights include:

● Earnings produced a return on average tangible common equity of 13.87% for the second quarter of 2022, compared to 14.14% in the previous quarter and 17.30% for the same quarter in the prior year (non-GAAP).

● Net interest income increased $1.0 million, or 5.1%, when compared to the previous quarter, and decreased $281 thousand, or 1.3%, when compared to the same quarter in 2021.

● Fully taxable equivalent (“FTE”) net interest margin was 2.76% for the quarter, up from 2.63% in the first quarter of 2022 and down from 3.00% in the same quarter of the prior year (non-GAAP).

● Noninterest revenues decreased $763 thousand, or 13.6%, when compared to the previous quarter, and decreased $305 thousand, or 5.9%, compared to the same quarter in the prior year.

● Noninterest expense increased $106 thousand, or less than 1%, when compared to the previous quarter, and increased $818 thousand, or 5.6%, when compared to the same quarter in the prior year.

● Average loans held for investment, excluding U.S. Small Business Administration Paycheck Protection Program (“PPP”) loans, grew $44.5 million, or 9.1% annualized, during the second quarter as compared to the previous quarter of $44.5 million, or 9.5% annualized.

● The Company recognized a provision for loan losses in the second quarter of 2022 of $581 thousand compared to negative provisions of $758 thousand in the first quarter of 2022 and $1.4 million in the second quarter of 2021. Annualized net charge-offs (recoveries) as a percentage of average loans outstanding were 0.01% for the second quarter of 2022, compared to (0.01%) in the previous quarter and the same quarter in the prior year.

● Nonperforming assets as a percentage of total assets were 0.05% at June 30, 2022, down from 0.06% at March 31, 2022, and down from 0.07% at June 30, 2021.

NET INTEREST INCOME

Net interest income for the second quarter of 2022 increased by $1.0 million, or 5.1%, to $21.5 million compared to $20.5 million for the first quarter of 2022. The second quarter of 2022 compared to the same quarter of 2021 reflected a decrease of $281 thousand, or 1.3%. The FTE net interest margin for the quarter was 2.76%, up from 2.63% in the prior quarter but down from 3.00% in the same quarter a year ago (non-GAAP). The margin expansion relative to the previous quarter was the product of a shift in the earning assets mix resulting from excess deposits in other banks being deployed into the loan and investment portfolios as well as higher yields on securities and deposits in other banks due to the increase in interest rates. The decrease in margin from second quarter 2021 was attributable to significantly more PPP related income in 2021, partially offset by lower interest expense.

The Company’s FTE net interest margin includes the impact of acquisition accounting fair value adjustments. During the second quarter of 2022, net accretion related to acquisition accounting amounted to $336 thousand compared to $566 thousand in the prior quarter and $875 thousand for the same quarter in 2021. Estimated remaining net accretion from acquisitions for the periods indicated is as follows (dollars in thousands):

For the years ending (estimated):
2022	$ 436
2023	719
2024	420
2025	298
2026	185
Thereafter	225

ASSET QUALITY

Nonperforming assets (“NPAs”) totaled $1.6 million as of June 30, 2022, down from $2.0 million at March 31, 2022, and down substantially from $2.4 million at June 30, 2021. NPAs as a percentage of total assets were 0.05% at June 30, 2022, compared to 0.06% at March 31, 2022 and 0.07% at June 30, 2021. The Company recorded a provision for loan losses for the second quarter of 2022 of $581 thousand compared to a recovery of provision of $758 thousand in the previous quarter and a recovery of provision of $1.4 million in the second quarter of the previous year. The provision expense for the second quarter of 2022 was a function of continued loan growth during the period and a slight increase in specific reserves. The increased provision expense as compared to the previous quarter and same quarter in 2021 was associated with downward adjustments in qualitative factors during those previous periods as the economy improved.

The allowance for loan losses was $18.5 million at June 30, 2022, compared to $18.0 million at March 31, 2022 and $20.1 million at June 30, 2021. Annualized net charge-offs (recoveries) as a percentage of average loans outstanding were 0.01% for the second quarter of 2022, compared to (0.01%) in both the previous quarter of 2022 and in the same quarter in the prior year. The allowance as a percentage of loans held for investment was 0.91% at June 30, 2022, compared to 0.90% at March 31, 2022, and 1.05% at June 30, 2021. Excluding PPP loans, the allowance as a percentage of loans was 0.91% at June 30, 2022 and March 31, 2022, compared to 1.11% at June 30, 2021.

NONINTEREST INCOME

Noninterest income decreased $763 thousand, or 13.6%, to $4.8 million for the quarter ended June 30, 2022 from $5.6 million in the prior quarter and decreased $305 thousand, or 5.9%, from the same quarter in the prior year. Mortgage banking and insurance were the primary contributors to this decline, with mortgage banking revenues contracting $244 thousand, or 36.3%, and income from insurance investments contracting $350 thousand, or 78.3%. Lower originations because of higher mortgage rates impacted mortgage banking income, and the decrease in income from insurance investments reflects a nonrecurring dividend of $350 thousand received in the first quarter of 2022.

The second quarter of 2022 compared to the second quarter of 2021 reflected a significant decrease in mortgage banking income, partially offset by growth in trust and brokerage fees, service charges on deposits, income from Small Business Investment Corporations and decreased losses on premises and equipment.

NONINTEREST EXPENSE

Noninterest expense for the second quarter of 2022 amounted to $15.5 million, up $106 thousand, or less than a 1% increase, when compared to $15.3 million for the previous quarter and up $818 thousand, or 5.6%, from $14.6 million during the same quarter in the previous year. The increase in the second quarter compared to the first quarter of 2022 was due to increased salary and benefits and other operational expenses.

The second quarter 2022 increase compared to the same quarter of 2021 was primarily due to increased salary and employee benefits expenses including incentive accruals, bank franchise taxes, data processing and other operational expenses.

INCOME TAXES

The effective tax rate for the three months ended June 30, 2022 was 20.90%, compared to 21.49% for the prior quarter and 21.00% for the same quarter in the prior year. The effective tax rate fluctuations are attributable to changes in pre-tax earnings and the levels of permanent tax differences.

BALANCE SHEET

Total assets at June 30, 2022 were $3.2 billion, a decrease of $112.5 million from March 31, 2022 and an increase of $32.1 million from June 30, 2021. The decrease from the previous quarter is due to lower interest bearing deposits in other banks resulting from a decrease in deposits, partially offset by the increase in loans, net during the period.

At June 30, 2022, loans held for investment (net of deferred fees and costs) were $2.0 billion, an increase of $42.8 million, or 8.6%, annualized from March 31, 2022. Loans held for investment, excluding PPP loans, increased $220.5 million, or 12.2%, from June 30, 2021.

Investment securities available for sale amounted to $668.8 million at June 30, 2022, a decrease of $17.4 million, or 2.5%, compared to March 31, 2022, and growth of $113.3 million, or 20.4%, compared to June 30, 2021.

Deposits amounted to $2.8 billion at June 30, 2022, a decrease of $95.9 million, or 13.1% annualized, from March 31, 2022 and growth of $60.6 million, or 2.2%, compared to June 30, 2021.

The Company continues to be well-capitalized as defined by regulators, with tangible common equity to tangible assets of 7.58% at June 30, 2022 compared to 7.54% at March 31, 2022 and compared to 8.27% at June 30, 2021 (non-GAAP). The Company’s common equity Tier 1, Tier 1, total, and Tier 1 leverage capital ratios were 12.02%, 13.24%, 14.06% and 9.42%, respectively, at June 30, 2022.

ABOUT AMERICAN NATIONAL

American National is a multi-state bank holding company with total assets of approximately $3.2 billion. Headquartered in Danville, Virginia, American National is the parent company of American National Bank and Trust Company. American National Bank is a community bank serving Virginia and North Carolina with 26 banking offices. American National Bank also manages an additional $1.1 billion of trust, investment and brokerage assets in its Wealth Division. Additional information about American National and American National Bank is available on American National's website at www.amnb.com.

NON-GAAP FINANCIAL MEASURES

This release contains financial information determined by methods other than in accordance with generally accepted accounting principles in the United States (“GAAP”). American National’s management uses these non-GAAP financial measures in its analysis of American National’s performance. These measures typically adjust GAAP performance measures to exclude the effects of the amortization of intangibles and include the tax benefit associated with revenue items that are tax-exempt, as well as adjust income available to common shareholders for certain significant activities or transactions that are infrequent in nature. Management believes presentations of these non-GAAP financial measures provide useful supplemental information that is essential to a proper understanding of the operating results of American National’s core businesses. These non-GAAP disclosures should not be viewed as a substitute for operating results determined in accordance with GAAP, nor are they necessarily comparable to non-GAAP performance measures that may be presented by other companies. For a reconciliation of non-GAAP financial measures, see “Reconciliation of Non-GAAP Financial Measures” at the end of this release.

FORWARD-LOOKING STATEMENTS

Statements made in this release, other than those concerning historical financial information, may be considered forward-looking statements, which speak only as of the date of this release and are based on current expectations and involve a number of assumptions. American National intends such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995 and is including this statement for purposes of these safe harbor provisions. American National’s ability to predict results, or the actual effect of future plans or strategies, is inherently uncertain. Factors that could have a material effect on the operations and future prospects of American National include but are not limited to: (1) the impacts of the ongoing COVID-19 pandemic and the associated efforts to limit the spread of the virus; (2) expected revenue synergies and cost savings from acquisitions and depositions; (3) changes in interest rates, general economic conditions, legislation and regulation, and monetary and fiscal policies of the U.S. government, including policies of the U.S. Treasury, Office of the Comptroller of the Currency and the Board of Governors of the Federal Reserve System; (4) the quality and composition of the loan and securities portfolios, demand for loan products, deposit flows, competition, and demand for financial services in American National’s market areas; (5) the adequacy of the level of the allowance for loan losses, the amount of loan loss provisions required in future quarters, and the failure of assumptions underlying the allowance for loan losses; (6) cybersecurity threats or attacks, the implementation of new technologies, and the ability to develop and maintain secure and reliable electronic systems; (7) accounting principles, policies, and guidelines; and (8) other risk factors detailed from time to time in filings made by American National with the Securities and Exchange Commission. American National undertakes no obligation to update or clarify these forward-looking statements, whether as a result of new information, future events or otherwise.

American National Bankshares Inc.

Consolidated Balance Sheets

(Dollars in thousands, except per share data)

Unaudited

	June 30,
ASSETS	2022			2021
Cash and due from banks	$	34,409		$	38,237
Interest-bearing deposits in other banks		307,164			502,300
Securities available for sale, at fair value		668,765			555,444
Restricted stock, at cost		8,495			8,035
Loans held for sale		5,227			13,807
Loans, net of deferred fees and costs		2,030,818			1,914,371
Less allowance for loan losses		(18,505	)		(20,097	)
Net Loans		2,012,313			1,894,274
Premises and equipment, net		34,878			37,478
Other real estate owned, net		143			213
Goodwill		85,048			85,048
Core deposit intangibles, net		3,977			5,339
Bank owned life insurance		29,318			28,791
Other assets		43,991			32,618
Total assets	$	3,233,728		$	3,201,584
Liabilities
Demand deposits -- noninterest-bearing	$	1,047,931		$	959,574
Demand deposits -- interest-bearing		544,323			482,586
Money market deposits		702,159			700,670
Savings deposits		275,945			241,746
Time deposits		259,989			385,174
Total deposits		2,830,347			2,769,750
Customer repurchase agreements		32,038			35,440
Long-term borrowings		28,283			28,181
Other liabilities		15,629			20,580
Total liabilities		2,906,297			2,853,951
Shareholders' equity
Preferred stock, $5 par, 2,000,000 shares authorized, none outstanding		—			—
Common stock, $1 par, 20,000,000 shares authorized, 10,663,599 shares outstanding at June 30, 2022 and 10,875,756 shares outstanding at June 30, 2021		10,588			10,811
Capital in excess of par value		143,337			150,947
Retained earnings		212,524			185,843
Accumulated other comprehensive (loss) income, net		(39,018	)		32
Total shareholders' equity		327,431			347,633
Total liabilities and shareholders' equity	$	3,233,728		$	3,201,584

American National Bankshares Inc.

Consolidated Statements of Income

(Dollars in thousands, except per share data)

Unaudited

	For the Three Months Ended									For the Six Months Ended
	6/30/22			3/31/22			6/30/21			6/30/22			6/30/21
Interest and Dividend Income:
Interest and fees on loans	$	19,076		$	18,788		$	21,087		$	37,864		$	43,360
Interest and dividends on securities:
Taxable		2,441			2,239			1,769			4,680			3,401
Tax-exempt		97			90			96			187			199
Dividends		116			113			117			229			236
Other interest income		800			177			98			977			175
Total interest and dividend income		22,530			21,407			23,167			43,937			47,371
Interest Expense:
Interest on deposits		646			569			922			1,215			2,209
Interest on short-term borrowings		9			6			5			15			16
Interest on long-term borrowings		385			379			469			764			952
Total interest expense		1,040			954			1,396			1,994			3,177
Net Interest Income		21,490			20,453			21,771			41,943			44,194
(Recovery of) provision for loan losses		581			(758	)		(1,352	)		(177	)		(1,352	)
Net Interest Income After (Recovery of) Provision for Loan Losses		20,909			21,211			23,123			42,120			45,546
Noninterest Income:
Trust and brokerage fees		1,587			1,809			1,490			3,396			2,914
Service charges on deposit accounts		709			689			630			1,398			1,252
Interchange fees		996			981			1,178			1,977			2,064
Other fees and commissions		200			266			180			466			433
Mortgage banking income		429			673			1,142			1,102			2,460
Income from Small Business Investment Companies		678			493			591			1,171			1,019
Income from insurance investments		97			447			141			544			929
Gains (losses) on premises and equipment, net		(84	)		4			(432	)		(80	)		(481	)
Other		225			238			222			463			474
Total noninterest income		4,837			5,600			5,142			10,437			11,064
Noninterest Expense:
Salaries and employee benefits		8,720			8,598			8,178			17,318			15,696
Occupancy and equipment		1,520			1,542			1,502			3,062			3,035
FDIC assessment		228			239			226			467			450
Bank franchise tax		488			476			443			964			881
Core deposit intangible amortization		320			330			371			650			752
Data processing		781			847			698			1,628			1,476
Software		363			363			338			726			667
Other real estate owned, net		2			(1	)		10			1			127
Other		3,033			2,955			2,871			5,988			5,618
Total noninterest expense		15,455			15,349			14,637			30,804			28,702
Income Before Income Taxes		10,291			11,462			13,628			21,753			27,908
Income Taxes		2,151			2,463			2,862			4,614			5,853
Net Income	$	8,140		$	8,999		$	10,766		$	17,139		$	22,055
Net Income Per Common Share:
Basic	$	0.76		$	0.84		$	0.99		$	1.60		$	2.02
Diluted	$	0.76		$	0.84		$	0.99		$	1.60		$	2.01
Weighted Average Common Shares Outstanding:
Basic		10,688,294			10,754,287			10,919,333			10,721,108			10,945,256
Diluted		10,690,496			10,756,902			10,923,156			10,723,517			10,949,523

American National Bankshares Inc.

Financial Highlights

Unaudited

(Dollars in thousands, except per share data)

	2nd Qtr			1st Qtr			2nd Qtr			At or for the Six Months Ended June 30,
	2022			2022			2021			2022			2021
EARNINGS
Interest income	$	22,530		$	21,407		$	23,167		$	43,937		$	47,371
Interest expense		1,040			954			1,396			1,994			3,177
Net interest income		21,490			20,453			21,771			41,943			44,194
(Recovery of) provision for loan losses		581			(758	)		(1,352	)		(177	)		(1,352	)
Noninterest income		4,837			5,600			5,142			10,437			11,064
Noninterest expense		15,455			15,349			14,637			30,804			28,702
Income taxes		2,151			2,463			2,862			4,614			5,853
Net income		8,140			8,999			10,766			17,139			22,055
PER COMMON SHARE
Net income per share - basic	$	0.76		$	0.84		$	0.99		$	1.60		$	2.02
Net income per share - diluted		0.76			0.84			0.99			1.60			2.01
Cash dividends paid		0.28			0.28			0.27			0.56			0.54
Book value per share		30.71			31.27			31.96			30.71			31.96
Book value per share - tangible (a)		22.36			22.94			23.65			22.36			23.65
Closing market price		34.61			37.68			31.09			34.61			31.09
FINANCIAL RATIOS
Return on average assets		0.99	%		1.08	%		1.38	%		1.04	%		1.44
Return on average common equity		9.83			10.24			12.44			10.04			12.81
Return on average tangible common equity (a)		13.87			14.14			17.30			14.01			17.87
Average common equity to average assets		10.06			10.59			11.10			10.32			11.20
Tangible common equity to tangible assets (a)		7.58			7.54			8.27			7.58			8.27
Net interest margin, taxable equivalent		2.76			2.63			3.00			2.70			3.10
Efficiency ratio (a)		57.18			57.53			52.06			57.35			49.84
Effective tax rate		20.90			21.49			21.00			21.21			20.97
PERIOD-END BALANCES
Securities	$	677,260		$	694,660		$	563,479		$	677,260		$	563,479
Loans held for sale		5,227			2,524			13,807			5,227			13,807
Loans, net		2,030,818			1,988,008			1,914,371			2,030,818			1,914,371
Goodwill and other intangibles		89,025			89,345			90,387			89,025			90,387
Assets		3,233,728			3,346,238			3,201,584			3,233,728			3,201,584
Assets - tangible (a)		3,144,703			3,256,893			3,111,197			3,144,703			3,111,197
Deposits		2,830,347			2,926,207			2,769,750			2,830,347			2,769,750
Customer repurchase agreements		32,038			38,527			35,440			32,038			35,440
Long-term borrowings		28,283			28,257			28,181			28,283			28,181
Shareholders' equity		327,431			335,074			347,633			327,431			347,633
Shareholders' equity - tangible (a)		238,406			245,729			257,246			238,406			257,246

American National Bankshares Inc.

Financial Highlights

Unaudited

(Dollars in thousands, except per share data)

	2nd Qtr			1st Qtr			2nd Qtr			At or for the Six Months Ended June 30,
	2022			2022			2021			2022			2021
AVERAGE BALANCES
Securities (b)	$	726,472		$	710,873		$	512,981		$	718,716		$	486,020
Loans held for sale		3,759			4,324			15,883			4,040			13,573
Loans, net		2,006,970			1,966,586			1,947,797			1,986,890			1,978,312
Interest-earning assets		3,120,925			3,126,561			2,909,216			3,123,728			2,862,016
Goodwill and other intangibles		89,200			89,525			90,577			89,362			90,775
Assets		3,292,913			3,320,314			3,118,687			3,306,538			3,073,073
Assets - tangible (a)		3,203,713			3,230,789			3,028,110			3,217,176			2,982,298
Interest-bearing deposits		1,849,664			1,880,873			1,761,203			1,865,182			1,750,867
Deposits		2,881,318			2,880,893			2,677,101			2,881,106			2,630,081
Customer repurchase agreements		35,766			41,337			37,591			38,536			40,651
Long-term borrowings		28,268			28,241			35,584			28,255			35,612
Shareholders' equity		331,276			351,539			346,210			341,352			344,232
Shareholders' equity - tangible (a)		242,076			262,014			255,633			251,990			253,457
CAPITAL
Weighted average shares outstanding - basic		10,688,294			10,754,287			10,919,333			10,721,108			10,945,256
Weighted average shares outstanding - diluted		10,690,496			10,756,902			10,923,156			10,723,517			10,949,523
COMMON STOCK REPURCHASE PROGRAM
Total shares of common stock repurchased		54,676			88,929			93,212			143,605			147,235
Average price paid per share of common stock	$	35.32		$	38.18		$	34.73		$	37.09		$	32.81
ALLOWANCE FOR LOAN LOSSES
Beginning balance	$	17,988		$	18,678		$	21,416		$	18,678		$	21,403
(Recovery of) provision for loan losses		581			(758	)		(1,352	)		(177	)		(1,352	)
Charge-offs		(117	)		(37	)		(29	)		(154	)		(51	)
Recoveries		53			105			62			158			97
Ending balance	$	18,505		$	17,988		$	20,097		$	18,505		$	20,097
LOANS
Construction and land development	$	174,361		$	148,276		$	133,592		$	174,361		$	133,592
Commercial real estate - owner occupied		403,478			402,306			384,095			403,478			384,095
Commercial real estate - non-owner occupied		749,174			752,817			650,862			749,174			650,862
Residential real estate		310,110			295,949			264,680			310,110			264,680
Home equity		95,352			89,593			100,835			95,352			100,835
Commercial and industrial		291,445			291,697			372,759			291,445			372,759
Consumer		6,898			7,370			7,548			6,898			7,548
Total	$	2,030,818		$	1,988,008		$	1,914,371		$	2,030,818		$	1,914,371

American National Bankshares Inc.

Financial Highlights

Unaudited

(Dollars in thousands, except per share data)

	2nd Qtr			1st Qtr			2nd Qtr			At or for the Six Months Ended June 30,
	2022			2022			2021			2022			2021
NONPERFORMING ASSETS AT PERIOD-END
Nonperforming loans:
90 days past due and accruing	$	90		$	71		$	125		$	90		$	125
Nonaccrual		1,385			1,762			2,057			1,385			2,057
Other real estate owned and repossessions		143			143			213			143			213
Nonperforming assets	$	1,618		$	1,976		$	2,395		$	1,618		$	2,395
ASSET QUALITY RATIOS
Allowance for loan losses to total loans		0.91	%		0.90	%		1.05	%		0.91	%		1.05	%
Allowance for loan losses to nonperforming loans		1,254.58			981.34			921.04			1,254.58			921.04
Nonperforming assets to total assets		0.05			0.06			0.07			0.05			0.07
Nonperforming loans to total loans		0.07			0.09			0.11			0.07			0.11
Annualized net recoveries to average loans		0.01			(0.01	)		(0.01	)		0.00			(0.00	)
OTHER DATA
Fiduciary assets at period-end (c) (d)	$	709,264		$	727,022		$	697,528		$	709,264		$	697,528
Retail brokerage assets at period-end (c) (d)	$	370,493		$	405,742		$	392,881		$	370,493		$	392,881
Number full-time equivalent employees (e)		345			338			340			345			340
Number of full service offices		26			26			26			26			26
Number of loan production offices		1			1			1			1			1
Number of ATMs		36			36			36			36			36

Notes:
(a) -	This financial measure is not calculated in accordance with GAAP. For a reconciliation of non-GAAP financial measures, see "Reconciliation of Non-GAAP Financial Measures" at the end of this release.
(b) -	Average does not include unrealized gains and losses.
(c) -	Market value.
(d) -	Assets are not owned by American National and are not reflected in the consolidated balance sheet.
(e) -	Average for quarter.

American National Bankshares Inc.

Net Interest Income Analysis

For the Three Months Ended June 30, 2022 and 2021

(Dollars in thousands)

Unaudited

					Interest
	Average Balance				Income/Expense (a)				Yield/Rate
	2022		2021		2022		2021		2022			2021
Loans:
Commercial	$	289,092	$	391,871	$	2,473	$	4,458		3.43	%		4.56	%
Real estate		1,715,073		1,564,747		16,538		16,551		3.86			4.23
Consumer		6,564		7,062		98		112		5.99			6.36
Total loans (b)		2,010,729		1,963,680		19,109		21,121		3.80			4.30
Securities:
U.S. Treasury		152,234		41,840		349		114		0.92			1.09
Federal agencies & GSEs		107,363		102,730		323		298		1.20			1.16
Mortgage-backed & CMOs		360,418		281,820		1,280		961		1.42			1.36
State and municipal		68,172		62,204		342		323		2.00			2.08
Other		38,285		24,387		385		311		2.01			5.10
Total securities		726,472		512,981		2,679		2,007		1.48			1.56
Deposits in other banks		383,724		432,555		800		98		0.84			0.09
Total interest-earning assets		3,120,925		2,909,216		22,588		23,226		2.90			3.20
Non-earning assets		171,988		209,471
Total assets	$	3,292,913	$	3,118,687
Deposits:
Demand	$	546,412	$	468,684		36		37		0.03			0.03
Money market		744,653		701,957		225		215		0.12			0.12
Savings		275,957		239,887		8		6		0.01			0.01
Time		282,642		350,675		377		664		0.54			0.76
Total deposits		1,849,664		1,761,203		646		922		0.14			0.21
Customer repurchase agreements		35,766		37,591		8		5		0.09			0.05
Long-term borrowings		28,268		35,584		377		469		5.33			5.27
Total interest-bearing liabilities		1,913,698		1,834,378		1,031		1,396		0.22			0.30
Noninterest bearing demand deposits		1,031,654		915,898
Other liabilities		16,285		22,201
Shareholders' equity		331,276		346,210
Total liabilities and shareholders' equity	$	3,292,913	$	3,118,687
Interest rate spread										2.68	%		2.90	%
Net interest margin										2.76	%		3.00	%
Net interest income (taxable equivalent basis)						21,557		21,830
Less: Taxable equivalent adjustment (c)						58		59
Net interest income					$	21,499	$	21,771

Notes:
(a) -	Interest income includes net accretion/amortization of acquired loan fair value adjustments and the net accretion/amortization of deferred loan fees and costs.
(b) -	Nonaccrual loans are included in the average balances.
(c) -	A tax rate of 21% was used in adjusting interest on tax-exempt assets to a fully taxable equivalent basis.

American National Bankshares Inc.

Net Interest Income Analysis

For the Six Months Ended June 30, 2022 and 2021

(Dollars in thousands)

Unaudited

					Interest
	Average Balance				Income/Expense (a)				Yield/Rate
	2022		2021		2022		2021		2022			2021
Loans:
Commercial	$	289,569	$	428,073	$	5,105	$	10,249		3.56	%		4.83	%
Real estate		1,694,825		1,556,465		32,616		32,941		3.85			4.23
Consumer		6,536		7,347		210		238		6.48			6.53
Total loans (b)		1,990,930		1,991,885		37,931		43,428		3.81			4.37
Securities:
U.S. Treasury		149,632		28,645		672		126		0.90			0.88
Federal agencies & GSEs		106,141		104,026		616		602		1.16			1.16
Mortgage-backed & CMOs		360,997		269,977		2,487		1,934		1.38			1.43
State and municipal		67,850		60,359		673		637		1.98			2.11
Other		34,096		23,013		697		588		4.09			5.11
Total securities		718,716		486,020		5,145		3,887		1.43			1.60
Deposits in other banks		414,082		384,111		977		175		0.48			0.09
Total interest-earning assets		3,123,728		2,862,016		44,053		47,490		2.82			3.32
Non-earning assets		182,810		211,057
Total assets	$	3,306,538	$	3,073,073
Deposits:
Demand	$	536,018	$	459,867		73		77		0.03			0.03
Money market		748,498		693,002		326		491		0.09			0.14
Savings		270,040		233,680		15		13		0.01			0.01
Time		310,626		364,318		801		1,628		0.52			0.90
Total deposits		1,865,182		1,750,867		1,215		2,209		0.13			0.25
Customer repurchase agreements		38,536		40,651		15		16		0.08			0.08
Long-term borrowings		28,255		35,612		764		952		5.41			5.35
Total interest-bearing liabilities		1,931,973		1,827,130		1,994		3,177		0.21			0.35
Noninterest bearing demand deposits		1,015,924		879,214
Other liabilities		17,289		22,497
Shareholders' equity		341,352		344,232
Total liabilities and shareholders' equity	$	3,306,538	$	3,073,073
Interest rate spread										2.61	%		2.97	%
Net interest margin										2.70	%		3.10	%
Net interest income (taxable equivalent basis)						42,059		44,313
Less: Taxable equivalent adjustment (c)						116		119
Net interest income					$	41,943	$	44,194

Notes:
(a) -	Interest income includes net accretion/amortization of acquired loan fair value adjustments and the net accretion/amortization of deferred loan fees and costs.
(b) -	Nonaccrual loans are included in the average balances.
(c) -	A tax rate of 21% was used in adjusting interest on tax-exempt assets to a fully taxable equivalent basis.

American National Bankshares Inc.

Reconciliation of Non-GAAP Financial Measures

Unaudited

(Dollars in thousands, except per share data)

	2nd Qtr			1st Qtr			2nd Qtr			At or for the Six Months Ended June 30,
	2022			2021			2021			2022			2021
EFFICIENCY RATIO
Noninterest expense	$	15,455		$	15,349		$	14,637		$	30,804		$	28,702
Subtract: loss on sale of OREO		—			—			—			—			(111	)
Subtract: core deposit intangible amortization		(320	)		(330	)		(371	)		(650	)		(752	)
	$	15,135		$	15,019		$	14,266		$	30,154		$	27,839
Net interest income	$	21,490		$	20,453		$	21,771		$	41,943		$	44,194
Tax equivalent adjustment		58			58			59			116			119
Noninterest income		4,837			5,600			5,142			10,437			11,064
Add/subtract: (gain)/loss on fixed assets		84			(4	)		432			80			481
	$	26,469		$	26,107		$	27,404		$	52,576		$	55,858
Efficiency ratio		57.18	%		57.53	%		52.06	%		57.35	%		49.84	%
TAX EQUIVALENT NET INTEREST INCOME
Non-GAAP measures:
Interest income - loans	$	19,109		$	18,822		$	21,121		$	37,931		$	43,428
Interest income - investments and other		3,479			2,643			2,105			6,122			4,062
Interest expense - deposits		(646	)		(569	)		(922	)		(1,215	)		(2,209	)
Interest expense - customer repurchase agreements		(8	)		(6	)		(5	)		(14	)		(16	)
Interest expense - long-term borrowings		(377	)		(379	)		(469	)		(756	)		(952	)
Total net interest income	$	21,557		$	20,511		$	21,830		$	42,068		$	44,313
Less non-GAAP measures:
Tax benefit on nontaxable interest - loans		(34	)		(34	)		(34	)		(68	)		(68	)
Tax benefit on nontaxable interest - securities		(24	)		(24	)		(25	)		(48	)		(51	)
GAAP measures	$	21,499		$	20,453		$	21,771		$	41,952		$	44,194
RETURN ON AVERAGE TANGIBLE EQUITY
Return on average equity (GAAP basis)		9.83	%		10.24	%		12.44	%		10.04	%		12.81	%
Impact of excluding average goodwill and other intangibles		4.04			3.90			4.86			3.97			5.06
Return on average tangible equity (non-GAAP)		13.87	%		14.14	%		17.30	%		14.01	%		17.87	%
TANGIBLE EQUITY TO TANGIBLE ASSETS
Equity to assets ratio (GAAP basis)		10.13	%		10.01	%		10.86	%		10.13	%		10.86	%
Impact of excluding goodwill and other intangibles		(2.55	)		(2.47	)		(2.59	)		(2.55	)		(2.59	)
Tangible equity to tangible assets ratio (non-GAAP)		7.58	%		7.54	%		8.27	%		7.58	%		8.27	%
TANGIBLE BOOK VALUE
Book value per share (GAAP basis)	$	30.71		$	31.27		$	31.96		$	30.71		$	31.96
Impact of excluding goodwill and other intangibles		(8.35	)		(8.33	)		(8.31	)		(8.35	)		(8.31	)
Tangible book value per share (non-GAAP)	$	22.36		$	22.94		$	23.65		$	22.36		$	23.65
ADJUSTED LOAN LOSS ALLOWANCE
Allowance for loan losses	$	18,505		$	17,988		$	20,097		$	18,505		$	20,097
Credit discount on purchased loans		3,741			4,001			6,055			3,741			6,055
Adjusted loan loss allowance	$	22,246		$	21,989		$	26,152		$	22,246		$	26,152
Total loans, net	$	2,030,818		$	1,988,008		$	1,914,371		$	2,030,818		$	1,914,371
Subtract: PPP loans, net		(116	)		(689	)		(104,143	)		(116	)		(104,143	)
Total loans less PPP loans, net	$	2,030,702		$	1,987,319		$	1,810,228		$	2,030,702		$	1,810,228
Adjusted loan loss allowance to total loans less PPP loans, net		1.10	%		1.11	%		1.44	%		1.10	%		1.44	%
Allowance for loan losses to total loans less PPP loans, net		0.91	%		0.91	%		1.11	%		0.91	%		1.11	%