LETTER 1 filename1.txt Mail Stop 4561 February 11, 2008 Neal A. Petrovich Senior Vice President and Chief Financial Officer American National Bankshares, Inc. 628 Main Street Danville, VA 24541 Re: American National Bankshares, Inc. Form 10-K for the Fiscal Year Ended December 31, 2006 Form 10-Q for the Fiscal Quarters Ended March 31, 2007, June 30, 2007 and September 30, 2007 File No. 0-12820 Dear Mr. Petrovich: We have completed our review of your Form 10-K and related filings and have no further comments at this time. Sincerely, Michael Clampitt Staff Attorney 2