Stockholders' Equity (Details Narrative) - USD ($)						1 Months Ended							2 Months Ended	3 Months Ended		6 Months Ended	12 Months Ended
	Nov. 09, 2018	Nov. 09, 2018	Oct. 02, 2018	Jul. 31, 2018	Aug. 31, 2015	Nov. 30, 2018	Oct. 31, 2018	Sep. 30, 2018	Jul. 31, 2018	May 31, 2018	Apr. 30, 2018	Sep. 30, 2017	May 31, 2018	Dec. 31, 2018	Jun. 30, 2018	Jun. 30, 2018	Dec. 31, 2018	Dec. 31, 2017	Mar. 31, 2014
Preferred stock, shares authorized														100,000			100,000	100,000
Preferred stock, par value														$ 0.01			$ 0.01	$ 0.01
Number of stock issued during the period, shares										51,988
Sale of preferred stock																	$ 13,891,543
Accrued dividends																	$ 1,064,141
Stock option granted during the period																	4,984,000
Common stock, shares outstanding														10,761,684			10,761,684	10,521,278
Number shares issued, value										$ 75,000
Repurchase of common stock																	$ 46,311
Loss on settlement of debt																	$ (810,219)
Warrants [Member]
Weighted average exercise price																	$ 0.79
Number of warrants expired																	339,702
Vaya Pharma LLC [Member]
Number of stock issued during the period, shares											210,084
Number shares issued, value											$ 250,000
Employee Stock Option [Member]
Stock option granted during the period														260,000
Robert Moscato Jr [Member]
Stock option granted during the period									1,500,000
Uli Hacksell [Member]
Stock option granted during the period									1,000,000
Erik Emerson [Member]
Stock option granted during the period									1,125,000
SVP of Operations [Member]
Stock option granted during the period									250,000
Eric Teague [Member]
Stock option granted during the period								450,000
Private Placement [Member ]
Number of stock issued during the period, shares											71.46
Warrants [Member]
Common stock exercise price, per share														$ 0.55			$ 0.55
Warrants outstanding														36,267,329			36,267,329
Fair value of warrants																	$ 1,494,469
Loss on settlement of debt																	$ 754,697
Adjustable warrants, shares														1,895,013			1,895,013
Warrants [Member] | Autotelic Inc. [Member]
Fair value of warrants																	$ 1,494,469
Loss on settlement of debt																	$ 754,697
Subscription Agreements [Member] | Private Placement [Member ]
Warrants to purchase of common stock shares										2,958,460			2,958,460
Sale of preferred stock													$ 12,200,000
Placement agent fees and estimated expenses													$ 2,000,000
Subscription Agreements [Member] | Warrants [Member]
Preferred stock, par value	$ 0.75	$ 0.75
Warrants to purchase of common stock shares	73,000	73,000		0.75					0.75
Common stock exercise price, per share				$ 0.55					$ 0.55
Asset Purchase Agreement [Member] | Novosom Verwaltungs GmbH [Member]
Number of stock issued during the period, shares										51,988
Settlement Agreement [Member] | Vuong Trieu, Ph.D [Member]
Repurchase of common stock			$ 250,000
Repurchase of common stock, shares			500,000
Series B Preferred Stock [Member]
Preferred stock designated, shares														1,000			1,000
Preferred stock shares outstanding
Series A Preferred Stock [Member]
Preferred stock designated, shares														90,000			90,000
Preferred stock shares outstanding
Series C Preferred Stock [Member]
Preferred stock designated, shares																			1,200
Preferred stock, par value														$ 5,000			$ 5,000
Preferred stock liquidation preference per share														5,100			$ 5,100
Preferred stock voting rights																	voting rights of 666.67 votes per share
Common stock at a conversion price, per share														$ 7.50			$ 7.50
Number of stock issued during the period, shares																	100	750
Series C Preferred Stock [Member] | Investor [Member]
Conversion of stock, shares converted												270				650
Number of stock issued during the period, shares												180,000				433,334
Series D Preferred Stock [Member]
Preferred stock designated, shares					220
Number of stock issued during the period, shares																	40	60
Series D Preferred Stock [Member] | Securities Purchase Agreement [Member]
Preferred stock, par value					$ 5,000
Preferred stock liquidation preference per share					$ 300
Preferred stock voting rights					voting rights of 1,250 votes per share
Common stock at a conversion price, per share					$ 4.00
Number of stock issued during the period, shares					275,000
Sale of stock, shares					220
Warrants to purchase of common stock shares					344,000
Common stock exercise price, per share					$ 4.00
Proceeds from exercise price of warrants to common stock					$ 1,100,000
Preferred stock stated dividend rate					5.00%
Series D Preferred Stock [Member] | Investor [Member]
Conversion of stock, shares converted										20
Number of stock issued during the period, shares										25,000
Series E Convertible Preferred Stock [Member]
Preferred stock, shares authorized														3,500			3,500	3,500
Preferred stock designated, shares											3,500
Preferred stock shares outstanding														3,488			3,488	0
Preferred stock, par value														$ 0.01			$ 0.01	$ 0.01
Accrued dividends																	$ 974,247
Proceeds from private placement										$ 12,200,000	$ 12,200,000				$ 12,200,000
Series E Convertible Preferred Stock [Member] | Subscription Agreements [Member]
Sale of stock, shares													2,812
Preferred stock stated dividend rate													8.00%
Series E Convertible Preferred Stock [Member] | Subscription Agreements [Member] | Warrants [Member]
Preferred stock, par value										$ 5,000			$ 5,000
Common stock at a conversion price, per share										$ 0.50			$ 0.50
Warrants to purchase of common stock shares										0.75			0.75
Common stock exercise price, per share										$ 0.55			$ 0.55
Warrant term										5 years			5 years
Series E Convertible Preferred Stock [Member] | Investor [Member]
Conversion of stock, shares converted							2
Number of stock issued during the period, shares							20,000
Series F Convertible Preferred Stock [Member]
Preferred stock, shares authorized														2,200			2,200	2,200
Preferred stock designated, shares				2,200					2,200
Preferred stock shares outstanding														381			381	0
Preferred stock, par value														$ 0.01			$ 0.01	$ 0.01
Accrued dividends																	$ 89,894
Proceeds from private placement				$ 1,400,000		$ 1,700,000			$ 1,700,000
Series F Convertible Preferred Stock [Member] | Subscription Agreements [Member]
Preferred stock, par value				$ 5,000					$ 5,000
Common stock at a conversion price, per share	$ 0.50	$ 0.50		$ 0.50					$ 0.50
Sale of stock, shares		73							308
Warrants to purchase of common stock shares	0.75	0.75		308,000					308,000
Common stock exercise price, per share	$ 0.55	$ 0.55		$ 0.55					$ 0.55
Preferred stock stated dividend rate									8.00%
Warrant term	5 years	5 years		5 years					5 years
Placement agent fees and estimated expenses		$ 310,000							$ 180,000
Proceeds from private placement									$ 1,400,000
Purchase price of preferred stock	$ 5,000	$ 5,000
Weighted average exercise price		$ 0.55
Series E Preferred Stock [Member]
Sale of stock, shares
Repurchase of common stock
Repurchase of common stock, shares																	9
Series E Preferred Stock [Member] | Warrants [Member]
Warrant issued													29,135,560
Fair value of warrants													$ 31,106,896
Series E Preferred Stock [Member] | Subscription Agreements [Member] | Private Placement [Member ]
Conversion of stock, shares converted							2
Number of stock issued during the period, shares							20,000
Common Stock [Member]
Common stock, shares outstanding														10,761,684			10,761,684
Series F Preferred Stock [Member]
Sale of stock, shares	73
Repurchase of common stock
Repurchase of common stock, shares
Series F Preferred Stock [Member] | Warrants [Member]
Warrant issued													3,238,500
Fair value of warrants													$ 1,492,464
Warrants [Member]
Common stock exercise price, per share										$ 0.55			$ 0.55
Warrant term										5 years			5 years
Warrants [Member] | Autotelic Inc. [Member]
Warrant issued													1,345,040
Accrued and unpaid fees													$ 739,772