X0306 4 2017-06-07 0 0000737207 Marina Biotech, Inc. MRNA 0001587074 Trieu Vuong C/O MARINA BIOTECH, INC. 17870 CASTLETON STREET, SUITE 250 CITY OF INDUSTRY CA 91748 1 1 1 0 Chairman of the Board Common Stock 2017-06-08 4 P 0 20000 0.39 A 11117141 D Common Stock 2017-06-07 4 P 0 2500 0.38 A 11097141 D Common Stock 862068 I See Footnote Common Stock 23123558 I See Footnote Common Stock 5255354 I See Footnote Common Stock 1928571 D Represents shares held by Lipomedics Inc., of which entity the reporting person serves as Chairman of the Board and Chief Operating Officer. Represents shares held by Autotelic LLC, of which entity the reporting person serves as Chief Executive Officer. Represents shares held by Autotelic Inc., of which entity the reporting person serves as Chairman of the Board. Represents shares issuable to the reporting person upon the conversion of a promissory note held by the reporting person (at an assumed conversion price of $0.28). /s/ Vuong Trieu 2017-06-08