X0202 4 2005-05-25 0 0000737207 NASTECH PHARMACEUTICAL CO INC NSTK 0001251780 WORMUTH DAVID E 3450 MONTE VILLA PARKWAY BOTHELL WA 98021 0 1 0 0 Sr Vice Pres., Operations Nastech Pharmaceutical Company Inc Common Stock 2005-05-25 4 A 0 7500 0.00 A 7500 D Nastech Pharmaceutical Company Inc Stock Options 11.54 2005-05-25 4 A 0 7500 11.54 A 2006-05-25 2015-05-25 Common Stock 7500 135000 D N/A - restricted stock award On May 25, 2005, the reporting person was granted (i) 7,500 restricted shares of common stock pursuant to the 2004 Stock Incentive Plan of Nastech Pharmaceutical Company Inc., and (ii) options to purchase 7,500 shares of common stock pursuant to the 2002 Stock Option Plan of Nastech Pharmaceutical Company Inc. The restricted shares and the options vest in three equal annual installments beginning on May 25, 2006. /s/ Gregory L. Weaver Gregory L. Weaver Attorney in Fact 2005-05-27