Exhibit 21

CNB FINANCIAL CORPORATION

Form 10-K For The Year Ended December 31, 2021

SUBSIDIARIES OF THE REGISTRANT

Name	Jurisdiction of Incorporation or Organization
CNB Bank	Banking Association Chartered in Pennsylvania Incorporated in Pennsylvania
CNB Securities Corporation	Investment Holding Company Incorporated in Delaware
Holiday Financial Services Corporation	Consumer Loan Company Incorporated in Pennsylvania
CNB Insurance Agency	Insurance and Annuity Agency Incorporated in Pennsylvania
CNB Risk Management, Inc.	Captive Insurance Company Incorporated in Delaware