0001752724-23-295128.txt : 20231228 0001752724-23-295128.hdr.sgml : 20231228 20231228092609 ACCESSION NUMBER: 0001752724-23-295128 CONFORMED SUBMISSION TYPE: NPORT-P PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20231031 FILED AS OF DATE: 20231228 DATE AS OF CHANGE: 20231228 PERIOD START: 20240131 FILER: COMPANY DATA: COMPANY CONFORMED NAME: VANGUARD SPECIALIZED FUNDS CENTRAL INDEX KEY: 0000734383 ORGANIZATION NAME: IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 0131 FILING VALUES: FORM TYPE: NPORT-P SEC ACT: 1940 Act SEC FILE NUMBER: 811-03916 FILM NUMBER: 231519723 BUSINESS ADDRESS: STREET 1: PO BOX 2600 STREET 2: V26 CITY: VALLEY FORGE STATE: PA ZIP: 19482 BUSINESS PHONE: 6106691000 MAIL ADDRESS: STREET 1: PO BOX 2600 STREET 2: V26 CITY: VALLEY FORGE STATE: PA ZIP: 19482 FORMER COMPANY: FORMER CONFORMED NAME: VANGUARD SPECIALIZED FUNDS/ DATE OF NAME CHANGE: 20011121 FORMER COMPANY: FORMER CONFORMED NAME: VANGUARD SPECIALIZED PORTFOLIOS INC DATE OF NAME 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Vanguard® Health Care Fund
Schedule of Investments (unaudited)
As of October 31, 2023
The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at www.sec.gov.
    Shares Market
Value
($000)
Common Stocks (98.2%)
Belgium (3.2%)
1 UCB SA 10,647,286 778,743
* Argenx SE 1,170,371 550,521
* Galapagos NV 1,175,458 39,109
      1,368,373
Brazil (0.0%)
*,2 Hapvida Participacoes e Investimentos SA 8,909,471 6,521
China (1.2%)
2 WuXi AppTec Co. Ltd. Class H 11,971,416 143,855
* Legend Biotech Corp. ADR 1,511,284 99,850
*,2 Wuxi Biologics Cayman Inc. 10,465,200 65,070
  Shandong Weigao Group Medical Polymer Co. Ltd. Class H 69,910,000 64,890
*,3 Zai Lab Ltd. ADR 1,995,154 50,278
* Zai Lab Ltd. 16,916,600 43,172
*,2 Remegen Co. Ltd. Class H 4,397,500 25,044
      492,159
Denmark (2.7%)
* Genmab A/S 2,088,852 590,483
  Novo Nordisk A/S Class B 3,386,878 326,753
* Ascendis Pharma A/S ADR 1,893,751 169,131
*,3 Genmab A/S ADR 2,285,855 64,918
      1,151,285
Italy (0.1%)
  DiaSorin SpA 552,359 49,504
Japan (8.1%)
  Daiichi Sankyo Co. Ltd. 43,976,590 1,133,901
1 Eisai Co. Ltd. 19,123,817 1,013,148
  Chugai Pharmaceutical Co. Ltd. 28,320,400 839,886
  Otsuka Holdings Co. Ltd. 7,660,100 257,731
  Terumo Corp. 6,976,400 190,862
  Asahi Intecc Co. Ltd. 2,023,500 34,000
      3,469,528
Switzerland (5.8%)
  Novartis AG (Registered) 21,909,275 2,051,137
  Alcon Inc. 3,393,208 242,873
* Sandoz Group AG 4,472,143 116,271
  Tecan Group AG (Registered) 236,453 68,051
      2,478,332
United Kingdom (6.6%)
  AstraZeneca plc 19,618,370 2,456,292
  GSK plc 11,995,095 213,834

    Shares Market
Value
($000)
* Immunocore Holdings plc ADR 2,085,568 92,599
  Genus plc 1,791,160 46,593
* Verona Pharma plc ADR 1,160,032 16,183
      2,825,501
United States (70.5%)
  Eli Lilly & Co. 6,162,883 3,413,806
  UnitedHealth Group Inc. 6,201,994 3,321,540
  Merck & Co. Inc. 20,479,587 2,103,254
  Pfizer Inc. 58,865,924 1,798,943
  Humana Inc. 2,265,222 1,186,274
  Elevance Health Inc. 2,560,815 1,152,597
  Abbott Laboratories 11,672,803 1,103,664
* Biogen Inc. 4,558,453 1,082,815
  Danaher Corp. 5,113,563 981,906
* Boston Scientific Corp. 18,544,793 949,308
  Thermo Fisher Scientific Inc. 2,108,134 937,635
* Alnylam Pharmaceuticals Inc. 5,524,903 838,680
  Stryker Corp. 3,019,829 816,018
* Vertex Pharmaceuticals Inc. 2,140,609 775,136
* Regeneron Pharmaceuticals Inc. 943,378 735,731
  Zoetis Inc. 4,469,317 701,683
  HCA Healthcare Inc. 2,796,119 632,314
* Centene Corp. 8,903,692 614,177
* Edwards Lifesciences Corp. 9,386,095 598,082
* Moderna Inc. 6,006,382 456,245
*,1 Apellis Pharmaceuticals Inc. 8,783,055 427,383
  Agilent Technologies Inc. 3,576,445 369,697
* agilon health Inc. 19,042,628 342,767
* IQVIA Holdings Inc. 1,797,052 324,961
  Laboratory Corp. of America Holdings 1,485,818 296,762
* Molina Healthcare Inc. 729,664 242,942
  Teleflex Inc. 1,217,493 224,932
* Acadia Healthcare Co. Inc. 3,047,446 224,018
* Waters Corp. 811,122 193,477
* Insulet Corp. 1,457,112 193,169
* Illumina Inc. 1,744,376 190,870
* United Therapeutics Corp. 842,593 187,780
* Alkermes plc 7,675,410 185,668
* Blueprint Medicines Corp. 2,857,677 168,203
* Exact Sciences Corp. 2,624,777 161,660
* Sarepta Therapeutics Inc. 2,283,656 153,713
* Karuna Therapeutics Inc. 900,108 149,967
* Align Technology Inc. 714,731 131,932
*,1 REVOLUTION Medicines Inc. 6,449,517 127,700
* Cytokinetics Inc. 3,334,530 116,242
* Vaxcyte Inc. 2,365,953 113,802
* Denali Therapeutics Inc. 5,100,454 96,042
* ImmunoGen Inc. 6,287,201 93,428
  Encompass Health Corp. 1,448,032 90,589
* Shockwave Medical Inc. 425,258 87,714
* Roivant Sciences Ltd. 9,572,139 82,703
* Evolent Health Inc. Class A 3,351,619 81,880
*,1 Sage Therapeutics Inc. 4,304,671 80,626
* Rocket Pharmaceuticals Inc. 4,092,055 74,066
* Ionis Pharmaceuticals Inc. 1,646,123 72,874
* Amicus Therapeutics Inc. 6,120,321 67,140
* Prothena Corp. plc 1,782,583 64,993
* Option Care Health Inc. 2,086,842 57,868

    Shares Market
Value
($000)
* Celldex Therapeutics Inc. 2,219,651 52,206
* PTC Therapeutics Inc. 2,749,139 51,546
* Surgery Partners Inc. 2,158,143 49,918
* Agios Pharmaceuticals Inc. 2,179,303 45,787
* Syndax Pharmaceuticals Inc. 3,092,082 43,536
* Privia Health Group Inc. 2,035,900 42,795
* Xenon Pharmaceuticals Inc. 1,281,157 39,716
* Intellia Therapeutics Inc. 1,534,651 38,443
* Morphic Holding Inc. 1,237,989 24,698
* TG Therapeutics Inc. 3,066,304 23,703
*,3 RayzeBio Inc. 1,198,440 23,250
* Kymera Therapeutics Inc. 1,442,019 16,828
*,3 MoonLake Immunotherapeutics 213,700 11,072
      30,140,874
Total Common Stocks (Cost $28,168,959) 41,982,077
Temporary Cash Investments (1.8%)
Money Market Fund (0.1%)
4,5 Vanguard Market Liquidity Fund, 5.420% 224,870 22,485
    Face
Amount
($000)
 
Repurchase Agreements (1.7%)
  Bank of America Securities, LLC, 5.300%, 11/1/23
(Dated 10/31/23, Repurchase Value $23,804,000, collateralized by U.S. Treasury Note/Bond 4.500%, 7/15/26, with a value of $24,276,000)
23,800 23,800
  Bank of Nova Scotia, 5.280%, 11/1/23
(Dated 10/31/23, Repurchase Value $96,214,000, collateralized by U.S. Treasury Bill 0.000%, 1/2/24–6/13/24, and U.S. Treasury Note/Bond 4.125%, 7/31/28, with a value of $98,138,000)
96,200 96,200
  Barclays Capital Inc., 5.300%, 11/1/23
(Dated 10/31/23, Repurchase Value $67,010,000, collateralized by U.S. Treasury Note/Bond 2.625%, 7/31/29, with a value of $68,340,000)
67,000 67,000
  BNP Paribas Securities Corp., 5.280%, 11/1/23
(Dated 10/31/23, Repurchase Value $73,511,000, collateralized by U.S Treasury Bill 0.000%, 1/2/24, U.S. Treasury Inflation Indexed Note/Bond 5.419%, 7/31/24, and U.S. Treasury Note/Bond 0.500%–4.625%, 11/15/24–8/15/50, with a value of $74,970,000) 
73,500 73,500
  BNP Paribas Securities Corp., 5.300%, 11/1/23
(Dated 10/31/23, Repurchase Value $72,911,000, collateralized by Fannie Mae 1.820%–6.859%, 12/1/30–10/1/53, Freddie Mac 2.000%–7.043%, 5/1/32–12/1/52, Ginnie Mae 2.500%–7.000%, 2/15/31–9/20/63, U.S. Treasury Bill 0.000%, 8/8/24–9/5/24, and U.S. Treasury Note/Bond 0.500%–4.125%, 4/30/26–10/31/27, with a value of $74,358,000) 
72,900 72,900
  Credit Agricole Securities, 5.280%, 11/1/23
(Dated 10/31/23, Repurchase Value $87,713,000, collateralized by U.S. Treasury Inflation Indexed Note/Bond 0.125%, 10/15/26, with a value of $89,454,000)
87,700 87,700
  HSBC Bank USA, 5.280%, 11/1/23
(Dated 10/31/23, Repurchase Value $49,007,000, collateralized by U.S. Treasury Bill 0.000%, 2/13/24–2/22/24, with a value of $49,980,000)
49,000 49,000

    Face
Amount
($000)
Market
Value
($000)
  HSBC Bank USA, 5.300%, 11/1/23
(Dated 10/31/23, Repurchase Value $59,709,000, collateralized by Fannie Mae 1.500%–6.500%, 9/1/29–5/1/58, Freddie Mac 2.000%–6.000%, 8/1/34–3/1/53, U.S. Treasury Bill 0.000%, 5/16/24, U.S. Treasury Inflation Indexed Note/Bond 2.375%–5.522%, 10/31/24–1/15/25, and U.S. Treasury Note/Bond 0.250%–2.500%, 11/15/23–12/31/24, with a value of $60,894,000) 
59,700 59,700
  JP Morgan Securities LLC, 5.290%, 11/1/23
(Dated 10/31/23, Repurchase Value $63,009,000, collateralized by U.S. Treasury Bill 0.000%, 12/19/23–3/21/24, and U.S. Treasury Note/Bond 0.125%–4.500%, 11/15/23–2/15/47, with a value of $64,260,000) 
63,000 63,000
  Natixis SA, 5.280%, 11/1/23
(Dated 10/31/23, Repurchase Value $48,507,000, collateralized by Federal Home Loan Bank 2.840%, 1/27/42, U.S. Treasury Inflation Indexed Note/Bond 0.125%–1.625%, 10/15/27–2/15/53, and U.S. Treasury Note/Bond 0.750%–4.500%, 7/31/24–5/15/46, with a value of $49,470,000) 
48,500 48,500
  Nomura International plc, 5.280%, 11/1/23
(Dated 10/31/23, Repurchase Value $57,708,000, collateralized by U.S. Treasury Inflation Indexed Note/Bond 0.125%–1.125%, 1/15/32–1/15/33, and U.S. Treasury Note/Bond 0.250%–4.000%, 12/15/24–4/30/30, with a value of $58,933,000) 
57,700 57,700
  RBC Capital Markets LLC, 5.290%, 11/1/23
(Dated 10/31/23, Repurchase Value $49,507,000, collateralized by U.S. Treasury Note/Bond 3.125%–3.625%, 8/31/27–3/31/28, with a value of $50,490,000)
49,500 49,500
      748,500
Total Temporary Cash Investments (Cost $770,983) 770,985
Total Investments (100.0%) (Cost $28,939,942) 42,753,062
Other Assets and Liabilities—Net (0.0%) 14,092
Net Assets (100%) 42,767,154
Cost is in $000.
* Non-income-producing security.
1 Considered an affiliated company of the fund as the fund owns more than 5% of the outstanding voting securities of such company.
2 Security exempt from registration under Rule 144A of the Securities Act of 1933. Such securities may be sold in transactions exempt from registration, normally to qualified institutional buyers. At October 31, 2023, the aggregate value was $240,490,000, representing 0.6% of net assets.
3 Includes partial security positions on loan to broker-dealers. The total value of securities on loan is $22,152,000.
4 Affiliated money market fund available only to Vanguard funds and certain trusts and accounts managed by Vanguard. Rate shown is the 7-day yield.
5 Collateral of $22,393,000 was received for securities on loan.
  ADR—American Depositary Receipt.
A. Security Valuation: Securities are valued as of the close of trading on the New York Stock Exchange (generally 4 p.m., Eastern time) on the valuation date. Equity securities are valued at the latest quoted sales prices or official closing prices taken from the primary market in which each security trades; such securities not traded on the valuation date are valued at the mean of the latest quoted bid and asked prices. Securities for which market quotations are not readily available, or whose values have been affected by events occurring before the fund’s pricing time but after the close of the securities’ primary markets, are valued by methods deemed by the valuation designee to represent fair value and subject to oversight by the board of trustees. These procedures include obtaining quotations from an independent pricing service, monitoring news to identify significant market- or security-specific events, and evaluating changes in the values of foreign market proxies (for example, ADRs, futures contracts, or exchange-traded funds), between the time the foreign markets close and the fund’s pricing time. When fair-value pricing is employed, the prices of securities used by a fund to calculate its net asset value may differ from quoted or

published prices for the same securities. Investments in Vanguard Market Liquidity Fund are valued at that fund's net asset value. Other temporary cash investments are valued using the latest bid prices or using valuations based on a matrix system (which considers such factors as security prices, yields, maturities, and ratings), both as furnished by independent pricing services.
B. Foreign Currency: Securities and other assets and liabilities denominated in foreign currencies are translated into U.S. dollars using exchange rates obtained from an independent third party as of the fund’s pricing time on the valuation date. Realized gains (losses) and unrealized appreciation (depreciation) on investment securities include the effects of changes in exchange rates since the securities were purchased, combined with the effects of changes in security prices. Fluctuations in the value of other assets and liabilities resulting from changes in exchange rates are recorded as unrealized foreign currency gains (losses) until the assets or liabilities are settled in cash, at which time they are recorded as realized foreign currency gains (losses).
C. Repurchase Agreements: The fund enters into repurchase agreements with institutional counterparties. Securities pledged as collateral to the fund under repurchase agreements are held by a custodian bank until the agreements mature, and in the absence of a default, such collateral cannot be repledged, resold, or rehypothecated. Each agreement requires that the market value of the collateral be sufficient to cover payments of interest and principal. The fund further mitigates its counterparty risk by entering into repurchase agreements only with a diverse group of prequalified counterparties, monitoring their financial strength, and entering into master repurchase agreements with its counterparties. The master repurchase agreements provide that, in the event of a counterparty's default (including bankruptcy), the fund may terminate any repurchase agreements with that counterparty, determine the net amount owed, and sell or retain the collateral up to the net amount owed to the fund. Such action may be subject to legal proceedings, which may delay or limit the disposition of collateral.
D.  Various inputs may be used to determine the value of the fund’s investments. These inputs are summarized in three broad levels for financial statement purposes. The inputs or methodologies used to value securities are not necessarily an indication of the risk associated with investing in those securities.
Level 1—Quoted prices in active markets for identical securities.
Level 2—Other significant observable inputs (including quoted prices for similar securities, interest rates, prepayment speeds, credit risk, etc.).
Level 3—Significant unobservable inputs (including the fund’s own assumptions used to determine the fair value of investments). Any investments valued with significant unobservable inputs are noted on the Schedule of Investments.
The following table summarizes the market value of the fund’s investments as of October 31, 2023, based on the inputs used to value them:
  Level 1
($000)
Level 2
($000)
Level 3
($000)
Total
($000)
Investments        
Assets        
Common Stocks—North and South America 30,147,395 30,147,395
Common Stocks—Other 492,959 11,341,723 11,834,682
Temporary Cash Investments 22,485 748,500 770,985
Total 30,662,839 12,090,223 42,753,062

E.  Certain of the fund’s investments are in companies that are considered to be affiliated companies of the fund because the fund owns more than 5% of the outstanding voting securities of the company or the issuer is another member of The Vanguard Group. Transactions during the period in securities of these companies were as follows:
    Current Period Transactions  
  Jan. 31,
2023
Market
Value
($000)
Purchases
at Cost
($000)
Proceeds
from
Securities
Sold
($000)
Realized
Net
Gain
(Loss)
($000)
Change in
Unrealized
App. (Dep.)
($000)
Income
($000)
Capital Gain
Distributions
Received
($000)
Oct. 31,
2023
Market
Value
($000)
2seventy bio Inc. 27,835 8,155 (166,975) 147,295
Agios Pharmaceuticals Inc. 151,775 68,756 (135,374) 98,142 NA1
Apellis Pharmaceuticals Inc. NA2 244,635 23,539 6,741 29,603 427,383
Eisai Co. Ltd. 1,152,216 47,189 23,329 310 (163,238) 10,564 1,013,148
Ironwood Pharmaceuticals Inc. Class A 125,592 113,327 (6,333) (5,932)
REVOLUTION Medicines Inc. NA2 81,752 (34,034) 127,700
Sage Therapeutics Inc. NA2 95,967 (77,704) 80,626
UCB SA 896,839 21,218 (4,083) (92,795) 11,227 778,743
Vanguard Market Liquidity Fund 669 NA3 NA3 (2) 1 22,485
Total 2,354,926 469,543 258,324 (305,716) (98,662) 21,791 2,450,085
1 Not applicable—at October 31, 2023, the security was still held, but the issuer was no longer an affiliated company of the fund.
2 Not applicable—at January 31, 2023, the issuer was not an affiliated company of the fund.
3 Not applicable—purchases and sales are for temporary cash investment purposes.