CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 584,640	$ 603,814
Accounts receivable, net of reserves of $1,364 and $1,417 at March 31, 2022 and December 31, 2021, respectively	122,435	117,420
Inventories, net	213,775	184,494
Prepaid expenses and other current assets	23,939	25,949
Total current assets	944,789	931,677
Property, plant and equipment, net	147,627	124,964
Intangible assets, net	329,928	337,274
Goodwill	859,488	860,362
Deferred tax assets	1,611	1,903
Operating lease right of use assets	99,750	101,559
Other noncurrent assets	631	615
Total noncurrent assets	1,439,035	1,426,677
Total assets	2,383,824	2,358,354
Current liabilities:
Accounts payable	38,280	36,203
Operating lease liability	9,882	8,303
Current contingent consideration	27,790	0
Accrued liabilities	65,114	75,498
Convertible senior notes, current portion, net	283,267	255,258
Total current liabilities	424,333	375,262
Deferred tax liabilities	25,858	33,480
Noncurrent operating lease liability	100,435	102,492
Noncurrent contingent consideration	64,037	94,238
Other noncurrent liabilities	2,760	2,815
Total noncurrent liabilities	193,090	233,025
Total liabilities	617,423	608,287
Commitments and contingencies (Note 9)
Stockholders' equity:
Preferred stock, $0.01 par value, 5,000,000 shares authorized, no shares issued or outstanding	0	0
Common stock, $0.01 par value; 80,000,000 shares authorized; 55429046 shares at March 31,2022 and 55321457 shares at December 31, 2021 issued and outstanding	554	553
Additional paid-in capital	1,529,144	1,572,340
Accumulated other comprehensive loss	(21,574)	(16,886)
Accumulated earnings	258,277	194,060
Total stockholders' equity	1,766,401	1,750,067
Total liabilities and stockholders' equity	$ 2,383,824	$ 2,358,354