X0303 4 2009-01-02 0000729922 OSI PHARMACEUTICALS INC OSIP 0001391045 Legault Pierre C/O OSI PHARMACEUTICALS, INC. 41 PINELAWN ROAD MELVILLE NY 11747 1 Exec. VP, CFO & Treasurer Common Stock 2009-01-02 4 A 0 12500 0 A 12500 D Stock Option (Right to Buy) 39.77 2009-01-02 4 A 0 125000 39.77 A 2012-01-02 2016-01-01 Common Stock 125000 125000 D Represents the Restricted Stock Unit component of the equity compensation awarded to Mr. Legault upon his appointment as an executive officer of the Company. 25% of the Restricted Stock Units vest one year after the date of grant and the remainder will vest ratably on an annual basis over the succeeding 3 years. Mr. Legault will receive one share of OSI Common Stock for each vested Restricted Stock Unit that he holds. One third of the stock option grant will become exercisable on each of the third, fourth and fifth anniversaries of the grant date. Includes only options with the same termination date. /s/ Pierre Legault 2009-01-05