424B3 1 y69486e424b3.txt FILED PURSUANT TO RULE 424(B)(3) FILED PURSUANT TO RULE 424(B)(3) AND (C) REGISTRATION NO. 333-110938 PROSPECTUS SUPPLEMENT NO. 1 DATED DECEMBER 13, 2004 $150,000,000 OSI PHARMACEUTICALS, INC. 3 1/4% CONVERTIBLE SENIOR SUBORDINATED NOTES DUE 2023 AND 2,998,800 SHARES OF COMMON STOCK ISSUABLE UPON CONVERSION OF THE NOTES This Prospectus Supplement relates to resales by selling securityholders of our 3.25% Convertible Senior Subordinated Notes due 2023 and shares of our common stock into which the notes are convertible. This Prospectus Supplement must be read in conjunction with the Prospectus dated October 18, 2004 (the "Prospectus"). SEE "RISK FACTORS," BEGINNING ON PAGE 9 OF THE PROSPECTUS AS THEY MAY BE MODIFIED AND INCORPORATED BY REFERENCE, TO READ ABOUT FACTORS YOU SHOULD CONSIDER BEFORE BUYING THE NOTES OR OUR COMMON STOCK. NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR DETERMINED IF THIS PROSPECTUS IS TRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE. The date of this Prospectus Supplement is December 13, 2004 SELLING SECURITYHOLDERS The information in the table appearing in the Prospectus under the heading "Selling Securityholders" is superseded by the information appearing in the following table:
NUMBER OF SHARES OF COMMON STOCK PRINCIPAL AMOUNT OF ISSUABLE UPON NOTES BENEFICIALLY PERCENTAGE OF CONVERSION OF THE PERCENTAGE OF OWNED THAT MAY BE NOTES NOTES THAT MAY BE COMMON STOCK SELLING SECURITYHOLDER+ OFFERED** OUTSTANDING(1) OFFERED(2) OUTSTANDING(3) ----------------------- ------------------- ------------------- ------------------- -------------- AIG DKR SoundShore Holdings Ltd......................... $ 1,172,000 * 23,430 * AIG DKR SoundShore Oasis Holding Fund Ltd............ $ 2,500,000 1.67% 49,980 * AIG DKR SoundShore Opportunity Holding Fund Ltd............ $ 824,000 * 16,473 * AIG DKR SoundShore Strategic Holding Fund Ltd............ $ 3,004,000 2.00% 60,055 * Alexandra Global Master Fund, Ltd......................... $10,000,000 6.67% 199,920 * Alta Partners Holdings LDC.... $10,000,000 6.67% 199,920 * Argent Classic Convertible Arbitrage Fund (Bermuda) Ltd......................... $ 5,860,000 3.91% 117,153 * Argent Classic Convertible Arbitrage Fund, L.P......... $ 1,590,000 1.06% 31,787 * Argent Classic Convertible Arbitrage Fund II, L.P...... $ 230,000 * 4,598 * Argent LowLev Convertible Arbitrage Fund Ltd.......... $ 3,000,000 2.00% 59,976 * Argent LowLev Convertible Arbitrage Fund LLC.......... $ 607,000 * 12,135 * Argent LowLev Convertible Arbitrage Fund II LLC....... $ 93,000 * 1,859 * Barclays Global Investors Equity Hedge Fund II(4)..... $ 43,000 * 859 * Cheyne Fund L.P............... $ 5,092,000 3.39% 101,799 * Cheyne Leveraged Fund L.P..... $ 4,560,000 3.04% 91,163 * CIP Limited Duration Company..................... $ 224,000 * 4,478 * Class C Trading Company, Ltd......................... $ 300,000 * 5,997 * CNH CA Master Account, L.P.... $ 2,000,000 1.33% 39,984 * Context Convertible Arbitrage Fund, LP(5)................. $ 2,500,000 1.67% 49,980 * Context Convertible Arbitrage Offshore, Ltd............... $ 2,350,000 1.57% 46,981 * Credit Suisse First Boston LLC(5)...................... $ 2,500,000 1.67% 49,980 * CS Alternative Strategy Ltd......................... $ 124,000 * 2,479 * DB Equity Opportunities Master Portfolio Ltd............... $ 800,000 * 15,993 * DBAG London(4)................ $11,400,000 7.60% 227,908 * Deutsche Bank Securities Inc.(5)..................... $ 3,000,000 2.00% 59,996 * DKR Saturn Event Driven Holding Fund Ltd............ $ 8,750,000 5.83% 174,930 *
41
NUMBER OF SHARES OF COMMON STOCK PRINCIPAL AMOUNT OF ISSUABLE UPON NOTES BENEFICIALLY PERCENTAGE OF CONVERSION OF THE PERCENTAGE OF OWNED THAT MAY BE NOTES NOTES THAT MAY BE COMMON STOCK SELLING SECURITYHOLDER+ OFFERED** OUTSTANDING(1) OFFERED(2) OUTSTANDING(3) ----------------------- ------------------- ------------------- ------------------- -------------- DKR Saturn Multi-Strategy Holding Fund Ltd. (Formerly Known As DKR Saturn Holding Fund Ltd.).................. $ 8,750,000 5.83% 174,930 * Excelsior Master Fund L.P..... $ 1,150,000 * 22,990 * Geode U.S. Convertible Arbitrage Fund.............. $ 5,000,000 3.33% 99,960 * GLG Market Neutral Fund....... $ 8,000,000 5.33% 159,936 * JP Morgan Securities Inc.(5)..................... $12,000,000 8.00% 239,904 * KBC Financial Products USA Inc.(5)..................... $ 2,300,000 1.53% 45,981 * KBC Financial Products (Cayman Islands) Ltd.(4)............ $ 5,000,000 3.33% 99,960 * LDG Limited................... $ 441,000 * 8,816 * Lexington Vantage Fund........ $ 25,000 * 499 * Lyxor Context Funds LTD(4).... $ 100,000 * 1,999 * Lyxor Master Fund, Ltd........ $ 500,000 * 9,996 * McMahan Securities Co. LP(5)....................... $ 100,000 * 1,999 * Mellon HBU Master Multi- Strategy Fund L.P.(4)....... $ 500,000 * 9,996 * Merrill Lynch Pierce Fenner & Smith(5).................... $ 500,000 * 9,996 * Morgan Stanley Convertible Securities Trust(4)......... $ 1,000,000 * 19,992 * National Bank of Canada....... $ 200,000 * 3,998 Polygon Global Opportunities Master Fund................. $ 5,000,000 3.33% 99,960 * Pyramid Equity Strategies Fund........................ $ 200,000 * 3,998 * Quattro Fund Ltd.............. $ 3,850,000 2.57% 76,969 * Quattro Multi Strategy Master Fund LP..................... $ 825,000 * 16,493 * Relay 3 Asset Holding Co. Limited..................... $ 27,000 * 539 * Royal Bank of Canada(4)....... $ 200,000 * 3,998 * Satellite Convertible Arbitrage Master Fund, LLC......................... $ 5,000,000 3.33% 99,960 * Scorpion Offshore Investment Fund, Ltd................... $ 231,000 * 4,618 * SP Holdings Ltd............... $ 58,000 * 1,159 * Sphinx Fund................... $ 41,000 * 819 * Standard Global Equity Partners L.P................ $ 842,000 * 16,833 * Standard Global Equity Partners II, L.P............ $ 40,000 * 799 * Standard Global Equity Partners SA, L.P............ $ 403,000 * 8,056 * Standard Pacific Capital Offshore Fund, Ltd.......... $ 3,196,000 2.13% 63,894 * Standard Pacific MAC 16 Ltd......................... $ 160,000 * 3,198 *
42
NUMBER OF SHARES OF COMMON STOCK PRINCIPAL AMOUNT OF ISSUABLE UPON NOTES BENEFICIALLY PERCENTAGE OF CONVERSION OF THE PERCENTAGE OF OWNED THAT MAY BE NOTES NOTES THAT MAY BE COMMON STOCK SELLING SECURITYHOLDER+ OFFERED** OUTSTANDING(1) OFFERED(2) OUTSTANDING(3) ----------------------- ------------------- ------------------- ------------------- -------------- TQA Master Fund, Ltd.......... $ 1,082,000 * 21,631 * TQA Master Plus Fund, Ltd..... $ 1,541,000 1.03% 30,807 * UBS O'Connor LLC.............. $ 500,000 * 9,996 * Univest Convertible Arbitrage Fund II LTD (Norshield)..... $ 100,000 * 1,999 * US Bancorp Piper Jaffray(5)... $ 3,000,000 2.00% 59,976 * WPG MSA Convertible Arbitrage Fund(4)..................... $ 100,000 * 1,999 * Xavex Convertible Arbitrage 10 Fund........................ $ 320,000 * 6,397 * Xavex Convertible Arbitrage 7 Fund........................ $ 262,000 * 5,237 * Zurich Institutional Benchmarks Management Fund........................ $ 825,000 * 16,493 * Zurich Institutional Benchmarks Master Fund, Ltd......................... $ 164,000 * 3,278 *
--------------- + Information about other selling securityholders will be set forth in post-effective amendments or, if permissible, prospectus supplements. Assumes that any other holders of the notes or any future pledges, donees, assignees, transferees or successors of or from any other such holders of the notes, do not beneficially own any shares of common stock other than the common stock issuable upon conversion of the notes at the initial conversion rate. * Represents less than one percent. ** Amounts indicated may be in excess of the total amount registered due to sales or transfers exempt from the registration requirements of the Securities Act of 1933, as amended, since the date upon which the selling securityholders provided to us the information regarding their notes. (1) Based upon $150,000,000 of 3 1/4% Convertible Senior Subordinated Notes outstanding. (2) Assumes conversion of all of the securityholders' notes at a conversion price of $50.02 per share. This conversion price is subject to adjustment, however, as described under "Description of the Notes - Conversion Rights." As a result, the number of shares of common stock issuable upon conversion of the notes may increase or decrease in the future. (3) Based upon 50,634,509 shares of common stock which is the number of shares of common stock outstanding as of December 1, 2004. (4) With respect to selling securityholders that are affiliates of broker-dealers, such entities have represented to us that they acquired their notes or underlying common stock in the ordinary course of business and, at the time of the purchase of the notes or the underlying common stock, such selling securityholders had no agreements or understandings, directly or indirectly, with any person to distribute the notes or underlying common stock. To the extent that we become aware that such entities did not acquire their notes or underlying common stock in the ordinary course of business or did have such an agreement or understanding, we will file a post-effective amendment to the registration statement of which this prospectus forms a part to designate such affiliate as an "underwriter" within the meaning of the Securities Act of 1933. (5) This selling securityholder has identified itself as a registered broker-dealer and, accordingly, it is deemed to be, under the interpretations of the Securities and Exchange Commission, an "underwriter" within the meaning of the Securities Act of 1933. Please see "Plan of Distribution" for required disclosure regarding these selling securityholders. 43