X0101 EFFECT 33 LIVE 2006-10-03 0000051931-06-000058 485APOS 0000729528 AMERICAN FUNDS INSURANCE SERIES 002-86838 S000008783 Global Discovery Fund C000023898 Class 1 S000008783 Global Discovery Fund C000023899 Class 2 S000008786 Global Growth Fund C000023903 Class 1 S000008786 Global Growth Fund C000023904 Class 2 S000008787 High-Income Bond Fund C000023905 Class 1 S000008787 High-Income Bond Fund C000023906 Class 2 S000008787 High-Income Bond Fund C000023907 Class 3 S000008788 U.S. Government/AAA-Rated Securities Fund C000023908 Class 1 S000008788 U.S. Government/AAA-Rated Securities Fund C000023909 Class 2 S000008788 U.S. Government/AAA-Rated Securities Fund C000023910 Class 3 S000008789 Cash Management Fund C000023911 Class 1 S000008789 Cash Management Fund C000023912 Class 2 S000008789 Cash Management Fund C000023913 Class 3 S000008790 Global Small Capitalization Fund C000023914 Class 1 S000008790 Global Small Capitalization Fund C000023915 Class 2 S000008791 Growth Fund C000023916 Class 1 S000008791 Growth Fund C000023917 Class 2 S000008791 Growth Fund C000023918 Class 3 S000008792 International Fund C000023919 Class 1 S000008792 International Fund C000023920 Class 2 S000008792 International Fund C000023921 Class 3 S000008793 New World Fund C000023922 Class 1 S000008793 New World Fund C000023923 Class 2 S000008794 Blue Chip Income and Growth Fund C000023924 Class 1 S000008794 Blue Chip Income and Growth Fund C000023925 Class 2 S000008795 Growth-Income Fund C000023926 Class 1 S000008795 Growth-Income Fund C000023927 Class 2 S000008795 Growth-Income Fund C000023928 Class 3 S000008796 Asset Allocation Fund C000023929 Class 1 S000008796 Asset Allocation Fund C000023930 Class 2 S000008796 Asset Allocation Fund C000023931 Class 3 S000008797 Bond Fund C000023932 Class 1 S000008797 Bond Fund C000023933 Class 2 S000013710 Global Growth and Income Fund C000037623 Class 1 S000013710 Global Growth and Income Fund C000037624 Class 2 S000013796 Global Bond Fund C000037827 Class 1 S000013796 Global Bond Fund C000037828 Class 2