American Funds Insurance Series

333 South Hope Street

Los Angeles, California  90071-1406

Phone (213) 486 9447

Fax (213) 486 9455

E-mail: siik@capgroup.com

Steven I. Koszalka

Secretary

December 27, 2012

Document Control

Division of Investment Management

Securities and Exchange Commission

Office of Insurance Products

100 F Street, NE

Washington, DC 20549

Re:	American Funds Insurance Series
	File No. 002-86838 and No. 811-03857

Dear Sir or Madam:

On behalf of the Series, transmitted for filing pursuant to Rule 497 under the Securities Act of 1933 are exhibits containing interactive data format risk/return summary information.

The interactive data files included as an exhibit to this filing relate to the form of prospectus filed with the Securities and Exchange Commission on December 5, 2012 pursuant to Rule 497 (Accession No. 0001537151-12-000039), which is incorporated by reference into this filing.

Sincerely,

/s/ Steven I. Koszalka

Steven I. Koszalka

cc:	Sally Samuel
	Division of Investment Management –
	Office of Insurance Products