X0306 4/A 2017-06-15 2017-06-29 0 0000728387 IsoRay, Inc. ISR 0001067569 LAVOY THOMAS C C/O ISORAY, INC. 350 HILLS STREET, STE 106 RICHLAND WA 99354 1 1 0 0 CEO Stock Options (right to buy) 0.69 2017-06-15 4 D 0 250000 0 D 2026-02-15 Common Stock 250000 0 D Stock Options (right to buy) 0.93 2017-06-15 4 D 0 100000 0 D 2026-06-21 Common Stock 100000 0 D Stock Options (right to buy) 0.605 2017-06-27 4 A 0 715000 0 A 2027-06-27 Common Stock 715000 0 D The three reported transactions involved a termination of outstanding options, resulting in the deemed cancellation of the old options and the grant of a new option. 25% vested as of 6/27/2017, and the remaining 75% will vest over the next three (3) years, commencing on 6/27/2018, until fully vested. Updating the address /s/ Thomas C. LaVoy 2017-06-29