X0306 4 2022-07-21 0000728387 Isoray, Inc. ISR 0001393007 Woods Lori A 350 HILLS STREET, SUITE 106 RICHLAND WA 99354 1 1 CEO Stock Options (right to buy) 0.33 2022-07-21 4 A 0 940000 0 A 2032-07-21 Common Stock 940000 1670000 D 25% vested as of 7/21/2022, and the remaining 75% will vest over the next three (3) years, commencing on 7/21/2023, until fully vested. /s/ Lori A. Woods 2022-07-28