Accounts Payable and Accrued Expenses (Details Textual) - USD ($)	1 Months Ended		3 Months Ended				12 Months Ended
	Mar. 31, 2018	Jan. 31, 2018	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Dec. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Mar. 31, 2017
Accounts Payable, Accrued Expenses and Other [Line Items]
Accrued Royalties											$ 770,000
Royalty Interest Rate							25.00%
Proceeds from Royalties Received		$ 88,000
Accrued Royalties, Current		$ 313,000	$ 439,000		$ 253,000		$ 439,000
Revenues					60,000		6,918,000	$ 8,379,000
Adjustments To Royalties Revenue				$ 280,000				313,000
Royalty [Member]
Accounts Payable, Accrued Expenses and Other [Line Items]
Decreases Of Royalty Revenues							280,000	877,000
Revenues			94,000	94,000	60,000
Merck [Member]
Accounts Payable, Accrued Expenses and Other [Line Items]
Royalty Withheld								1,600,000	$ 1,600,000
Due to Related Parties			$ 225,000				$ 225,000		770,000
Decreases Of Royalty Revenues				$ 150,000		$ 111,000			$ 564,000	$ 564,000
Increase (Decrease) in Other Receivables	$ 313,000
Accrued Royalties, Current					$ 253,000	$ 313,000		313,000
Adjustments To Royalties Revenue								88,000
Merck [Member] | Royalty [Member]
Accounts Payable, Accrued Expenses and Other [Line Items]
Revenues								$ 1,300,000