CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Revenues:
Royalties	$ 8,044	$ 9,771	$ 17,608	$ 20,092
Contract research and development	0	33	0	136
Miscellaneous income	12	427	631	604
Total revenues	8,056	10,231	18,239	20,832
Operating expenses:
Research and development - pipeline	294	5,673	1,872	12,587
Research and development - specialty and contracted services	0	28	0	113
General and administrative	2,398	4,358	5,347	8,033
Restructuring charges	464	(70)	2,970	(107)
Total operating expenses	3,156	9,989	10,189	20,626
Operating income	4,900	242	8,050	206
Other income (expense):
Investment income, net	103	523	530	1,001
Interest expense	(850)	(1,364)	(2,124)	(2,781)
Other, net	646	(97)	866	(193)
Total other expense	(101)	(938)	(728)	(1,973)
Income (loss) before income tax expense	4,799	(696)	7,322	(1,767)
Income tax expense	80	33	213	33
Net income (loss)	4,719	(729)	7,109	(1,800)
Earnings (loss) per common share
Basic (in dollars per share)	$ 0.11	$ (0.02)	$ 0.16	$ (0.04)
Diluted (in dollars per share)	$ 0.09	$ (0.02)	$ 0.14	$ (0.04)
Weighted-average shares - basic (in shares)	43,729	48,176	43,711	48,234
Weighted-average shares - diluted (in shares)	55,272	48,176	58,197	48,234
Special cash dividend paid per common share	$ 1.60	$ 0	$ 1.60	$ 0
Other comprehensive income (loss):
Unrealized holding gains (losses) arising during period	(3)	(57)	234	480
Reclassification adjustment for realized losses (gains) on sales included in net income (loss)	(39)	(16)	(320)	19
Total other comprehensive income (loss)	(42)	(73)	(86)	499
Comprehensive income (loss)	$ 4,677	$ (802)	$ 7,023	$ (1,301)