FORM 5 U.S. SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Check this box if no longer subject to Section 16. Form 4 Filed pursuant to Section 16(a) of the or Form 5 obligations Securities Act of 1934, Section 17(a) of the Public may continue. SEE Utility Holding Company Act of 1935 or Section 30(f) Instruction1. of the Investment Company Act of 1940 Form 3 Holdings Reported Form 4 Transactions Reported

1. Name and Address of Reporting Person 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person to Issuer ENZON, INC. (ENZN) (Check all applicable) ZUERBLIS KENNETH J. Director ______ 10% Owner (Last) (First) (Middle) 3. IRS or Social 4. Statement for X Officer ______ Other Security Number of Month/Year (give title below) 40 JACKIE DRIVE Reporting Person JUNE 30, 1995 (specify below) (Voluntary) Vice President, Finance and Chief Financial Officer (Street) 5. If Amendment, Date of Original (Month/Year) LONG VALLEY NJ 07853 (City) (State) (Zip) TABLE I - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED 1. Title of Security 2. Trans- 3. Trans- 4. Securities Acquired 5. Amount of 6. Owner- 7. Nature of (Instr. 3) action action (A) or Disposed of Securities ship Indirect Date Code (D) Beneficially Form: Beneficial (Month/ (Instr. (Instr. 3, 4 and 5) Owned at End (D) or Ownership Day/ 8) of Issuer's Indirect (Instr. Year) Fiscal Year (I) 4) (Instr. 3 (Instr. and 4) 4) Amount (A) or Price (D)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Over) FORM 5 (CONTINUED) TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED (E.G., puts, calls, warrants, options, convertible securities)

1. Title of Derivative 2.Conver-3.Trans-4.Transac-5.Number of6.Date 7.Title and Amount of 8.Price9.Number10. 11. Na- Security sion action tion Deriv- ExercisableUnder-lying of of Owner- ture (Instru. 3) or Date Code ative and Securities (Instr. 3 Deriv-Deriv- ship of In- Exercise(Month/Day/(Instr.SecuritiesExpirationand 4) ative ative of De- direct Price Year)8) Ac- Date Secur-Secur- Bene- of quired (A) (Month/Day/ ity ities rivative ficial Deriv- or Disposed Year) (Instr.Bene- Own- ative of (D) 5) ficially Security: ership Security (Instr. 3, Owned (D) (Instr. 4) 4, and 5) at or In- End of Direct Year (Instr. (I)(Instr. 4) 4) (A) (D) Date Expira- Title Amount Exer- tion or cisableDate Number of Shares STOCK OPTION (RIGHT TO $2.09 1/20/95A 40,000 1/20/971/20/05COMMON STOCK 40,000 $2.09 40,000 D -- PURCHASE)+ STOCK OPTION (RIGHT TO $2.63 8/24/94A 45,000 8/24/968/24/04Common Stock 45,000 $2.63 45,000 D -- PURCHASE)+

Explanation of Responses: + Granted under the Company's Non-Qualified Stock Option Plan, as amended, a Rule 16b-3 plan. ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. /S/KENNETH J. ZUERBLIS 2/23/96 SEE 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). **Signature of Reporting Person Date Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, SEE Instruction 6 for procedure.