CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Revenues:
Royalties	$ 9,172	$ 10,588	$ 20,934	$ 23,489
Sale of in-process research and development	0	0	5,000	40,900
Contract research and development	231	2,602	1,325	5,211
Miscellaneous revenue	196	527	362	2,277
Total revenues	9,599	13,717	27,621	71,877
Operating expenses:
Research and development – pipeline	10,061	10,131	20,609	21,646
Research and development – specialty and contracted services	184	1,759	831	4,818
General and administrative	4,627	5,772	9,713	15,611
General and administrative – contracted services	54	421	112	1,821
Restructuring charge	674	710	1,033	10,599
Total operating expenses	15,600	18,793	32,298	54,495
Operating (loss) income	(6,001)	(5,076)	(4,677)	17,382
Other income (expense):
Investment income, net	386	811	845	1,782
Interest expense	(1,479)	(1,480)	(2,959)	(4,156)
Other, net	31	(31)	159	(30)
Total other expense	(1,062)	(700)	(1,955)	(2,404)
(Loss) income from continuing operations, before income tax expense (benefit)	(7,063)	(5,776)	(6,632)	14,978
Income tax expense (benefit)	5	(205)	5	(205)
(Loss) income from continuing operations	(7,068)	(5,571)	(6,637)	15,183
(Loss) income and gain from discontinued operations, net of income tax	0	(51)	0	179,002
Net (loss) income	$ (7,068)	$ (5,622)	$ (6,637)	$ 194,185
Earnings (loss) per common share - continuing operations
Basic (in Dollars per share)	$ (0.13)	$ (0.09)	$ (0.12)	$ 0.27
Diluted (in Dollars per share)	$ (0.13)	$ (0.09)	$ (0.12)	$ 0.23
Earnings per common share – discontinued operations
Basic (in Dollars per share)	$ 0	$ 0	$ 0	$ 3.16
Diluted (in Dollars per share)	$ 0	$ 0	$ 0	$ 2.38
Earnings (loss) per common share – net (loss) income
Basic (in Dollars per share)	$ (0.13)	$ (0.09)	$ (0.12)	$ 3.43
Diluted (in Dollars per share)	$ (0.13)	$ (0.09)	$ (0.12)	$ 2.61
Weighted average shares – basic (in Shares)	53,054	60,849	55,368	56,640
Weighted average shares - diluted (in Shares)	53,054	60,849	55,368	75,209