Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Cash flows from operating activities:
Net loss	$ (19,574)	$ (16,837)	$ (15,899)
Adjustments to reconcile net loss to net cash
Depreciation	350	365	344
Amortization of deferred loan costs	108	72	42
Amortization of debt discount	3,123	2,372	1,918
Interest added to loan principal	3,589	3,261	2,782
Unrealized (gain) loss on derivative liability		(108)	110
Compensation charge for stock awards and share options	383	2,376	4,009
Changes in operating assets and liabilities:
(Increase) decrease in accounts receivable	(121)	138	(102)
Decrease (increase) in prepaid expenses and other	200	(305)	63
(Increase) decrease in other assets	(109)	63	220
Increase (decrease) in accounts payable	128	304	(141)
Increase (decrease) in accrued liabilities	273	285	(107)
Increase in deferred revenue	250	500
Net cash used for operating activities	(11,400)	(7,514)	(6,761)
Cash flows from investing activities:
Additions to property, plant and equipment	(3,226)	(4,140)	(1,184)
Other Assets (restricted cash)	(63)
Net cash used for investing activities	(3,289)	(4,140)	(1,184)
Cash flows from financing activities:
Net proceeds from issuance of common stock		15,129
Proceeds from issuance of long-term debt	5,014	2,000	5,000
Principal payments on long-term debt	(10)	(16)	(22)
Net cash provided by financing activities	5,004	17,113	4,978
Net increase (decrease) in cash and cash equivalents	(9,685)	5,459	(2,967)
Cash and cash equivalents, beginning of period	11,370	5,911	8,878
Cash and cash equivalents, end of period	$ 1,685	$ 11,370	$ 5,911