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ORGANIZATION AND NATURE OF BUSINESS; BASIS OF PRESENTATION; PRINCIPLES OF CONSOLIDATION (Details)
1 Months Ended 12 Months Ended
Jan. 23, 2024
USD ($)
Jul. 11, 2023
Aug. 31, 2024
USD ($)
May 31, 2024
USD ($)
Mar. 31, 2023
Apr. 30, 2018
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Aug. 08, 2024
USD ($)
Aug. 31, 2023
Jun. 30, 2023
USD ($)
Jun. 09, 2023
Mar. 15, 2023
Mar. 31, 2018
USD ($)
Organization, Consolidation and Presentation of Financial Statements [Abstract]                            
Reverse stock split ratio   0.1                        
Accumulated deficit             $ 718,899,000 $ 668,857,000            
Net loss             50,045,000 61,618,000            
Net cash used in operating activities             24,194,000 40,196,000            
Working capital             9,000,000.0              
Debt Instrument [Line Items]                            
Proceeds from issuance of 16.00% Notes             15,000,000 0            
Cash and cash equivalents and investments             $ 16,300,000 13,200,000            
Decrease in cash and cash equivalents and investments               $ 3,100,000            
Jack W. Schuler Living Trust                            
Debt Instrument [Line Items]                            
Net proceeds $ 11,000,000     $ 2,700,000                    
2.50% Convertible Notes due 2023 | Convertible Notes                            
Debt Instrument [Line Items]                            
Interest rate (as a percent)               2.50%         2.50% 2.50%
Aggregate principal amount               $ 700,000           $ 150,000,000
Proceeds from issuance of 16.00% Notes           $ 171,500,000                
5.00% Convertible Notes Due 2026 | Convertible Notes                            
Debt Instrument [Line Items]                            
Interest rate (as a percent)     5.00%       5.00% 5.00%   5.00% 5.00% 5.00%    
Aggregate principal amount                     $ 10,000,000      
5.00% Convertible Notes Due 2026 | Senior Notes                            
Debt Instrument [Line Items]                            
Interest rate (as a percent)                     5.00%      
Aggregate principal amount                     $ 66,900,000      
16.00% Super-Priority Senior Secured PIK Notes Due 2025 | Senior Notes                            
Debt Instrument [Line Items]                            
Interest rate (as a percent)     16.00%       16.00%              
Aggregate principal amount     $ 15,000,000           $ 15,000,000          
Proceeds from issuance of 16.00% Notes     $ 14,200,000                      
Ad Hoc Noteholder Group | Lender | Outstanding Notes                            
Debt Instrument [Line Items]                            
Risk concentration (as a percent)         85.00%