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ORGANIZATION AND NATURE OF BUSINESS; BASIS OF PRESENTATION; PRINCIPLES OF CONSOLIDATION (Details)
1 Months Ended 12 Months Ended
Jan. 23, 2024
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Jul. 11, 2023
Jun. 09, 2023
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Apr. 21, 2023
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Mar. 13, 2023
Jan. 31, 2024
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Mar. 31, 2023
Aug. 31, 2022
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Sep. 30, 2021
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Dec. 31, 2023
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Dec. 31, 2022
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Dec. 31, 2021
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Jun. 30, 2023
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Mar. 31, 2022
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Mar. 31, 2018
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Organization, Consolidation and Presentation of Financial Statements [Abstract]                              
Reverse stock split ratio   0.1                          
Accumulated deficit                   $ 668,857,000 $ 607,239,000        
Net loss                   61,618,000 62,493,000 $ 77,702,000      
Net cash used in operating activities                   40,196,000 48,728,000 47,323,000      
Working capital                   12,400,000          
Debt Instrument [Line Items]                              
2.50% Notes extinguished in connection with exchange transaction                   0 49,624,000 $ 0      
Accrued interest, related-party                   0 663,000        
Net proceeds                   13,600,000          
Cash and cash equivalents and investments                   13,200,000 $ 45,600,000        
Decrease in cash and cash equivalents and investments                   $ 32,400,000          
Restructuring Support Agreement | Related Party | Series A Preferred Stock                              
Debt Instrument [Line Items]                              
Conversion of stock, shares converted (in shares) | shares     400,000                        
Jack W. Schuler Living Trust | Affiliated Entity | Series A Preferred Stock                              
Debt Instrument [Line Items]                              
Conversion of stock, shares converted (in shares) | shares                 4,000,000            
Outstanding notes | Lender | Ad Hoc Noteholder Group                              
Debt Instrument [Line Items]                              
Risk concentration (as a percent)         85.00%   85.00%                
March 2022 Securities Purchase Agreement | Jack W. Schuler Living Trust | Affiliated Entity                              
Debt Instrument [Line Items]                              
Sale of stock (in shares) | shares     500,000                        
Restructuring Support Agreement | Jack W. Schuler Living Trust | Affiliated Entity                              
Debt Instrument [Line Items]                              
Aggregate purchase price     $ 10,000,000                        
Public offering backstop     10,000,000                   $ 10,000,000    
Restructuring Support Agreement | Jack W. Schuler Living Trust | Affiliated Entity | Common Shares                              
Debt Instrument [Line Items]                              
Aggregate purchase price                         10,000,000    
Private Placement | March 2022 Securities Purchase Agreement | Jack W. Schuler Living Trust | Affiliated Entity                              
Debt Instrument [Line Items]                              
Net proceeds     4,000,000                        
Aggregate purchase price                           $ 4,000,000  
Subsequent Event | Public and Private Placement Offerings                              
Debt Instrument [Line Items]                              
Sale of stock (in shares) | shares           8,100,000                  
Net proceeds           $ 12,300,000                  
Subsequent Event | Public and Private Placement Offerings | Common Shares                              
Debt Instrument [Line Items]                              
New issues per offering unit (in shares) | shares           1                  
Number of securities called by each warrants (in shares) | shares           1                  
Subsequent Event | Public and Private Placement Offerings | Shares issuable upon the exercise of the Warrant                              
Debt Instrument [Line Items]                              
New issues per offering unit (in shares) | shares           1                  
Subsequent Event | Private Placement | Schuler Purchase Obligation | Jack W. Schuler Living Trust                              
Debt Instrument [Line Items]                              
Sale of stock (in shares) | shares 1,200,000                            
2.50% Convertible Notes due 2023 | Convertible Notes                              
Debt Instrument [Line Items]                              
Interest rate         2.50%                   2.50%
Accrued interest, related-party     1,000,000                        
Aggregate principal amount                         $ 10,000,000   $ 150,000,000
2.50% Convertible Notes due 2023 | Convertible Notes | Restructuring Support Agreement                              
Debt Instrument [Line Items]                              
Aggregate principal amount exchanged     55,900,000                        
Accrued interest, related-party     $ 1,000,000                        
2.50% Convertible Notes due 2023 | Convertible Notes | August 2022 Exchange Transaction | Jack W. Schuler Living Trust                              
Debt Instrument [Line Items]                              
Aggregate principal amount exchanged               $ 49,900,000              
5.00% Convertible Notes Due 2026 | Convertible Notes                              
Debt Instrument [Line Items]                              
Interest rate     5.00%                   5.00%    
5.00% Convertible Notes Due 2026 | Convertible Notes | Restructuring Support Agreement                              
Debt Instrument [Line Items]                              
2.50% Notes extinguished in connection with exchange transaction     $ 56,900,000                        
Aggregate principal amount     $ 10,000,000                        
Restructuring Support Agreement | Senior Notes | Affiliated Entity                              
Debt Instrument [Line Items]                              
Shares issued (in shares) | shares     3,400,000                        
Five Point Zero Percent Secured Promissory Note | Senior Notes | Jack W. Schuler Living Trust | Affiliated Entity                              
Debt Instrument [Line Items]                              
2.50% Notes extinguished in connection with exchange transaction     $ 25,400,000                        
Shares issued (in shares) | shares     3,400,000                        
Five Point Zero Percent Secured Promissory Note | Senior Notes | Jack W. Schuler Living Trust | August 2022 Exchange Transaction | Affiliated Entity                              
Debt Instrument [Line Items]                              
Aggregate principal amount exchanged       $ 34,900,000       $ 34,900,000