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INCOME TAXES - Narrative (Details) - USD ($)
$ in Thousands
12 Months Ended
Aug. 15, 2022
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jan. 01, 2022
Dec. 31, 2019
Dec. 31, 2018
Operating Loss Carryforwards [Line Items]              
Valuation allowance   $ 138,710 $ 131,839        
Initial deferred tax liability related to 2018 convertible debt   24 2,933        
Convertible notes due from related-party extinguished in connection with the exchange transaction, net of deferred issuance costs   49,624 0 $ 0      
Capital contribution from related-party in connection with exchange transaction   29,847          
Unrecognized tax benefits   13,596 7,556 $ 4,866   $ 3,712  
Uncertain tax positions that would impact the effective tax rate   100          
August 2022 Exchange Transaction | Jack W. Schuler Living Trust | Embeded Warrant              
Operating Loss Carryforwards [Line Items]              
Warrants fair value $ 3,800            
August 2022 Exchange Transaction | Jack W. Schuler Living Trust | Embeded Warrant | Level 3              
Operating Loss Carryforwards [Line Items]              
Warrants fair value 3,800            
Cumulative impact of accounting change | Accounting Standards Update 2020-06              
Operating Loss Carryforwards [Line Items]              
Initial deferred tax liability related to 2018 convertible debt         $ (3,000)    
Total convertible notes         $ 11,500    
Convertible Notes | 2.50% Convertible Notes due 2023              
Operating Loss Carryforwards [Line Items]              
Total convertible notes   56,413 $ 107,984        
Convertible Notes | August 2022 Exchange Transaction | 2.50% Convertible Notes due 2023 | Jack W. Schuler Living Trust              
Operating Loss Carryforwards [Line Items]              
Convertible notes due from related-party extinguished in connection with the exchange transaction, net of deferred issuance costs 49,900            
PPP Loan              
Operating Loss Carryforwards [Line Items]              
Initial deferred tax liability related to 2018 convertible debt             $ 14,000
Senior Notes | August 2022 Exchange Transaction | Five Point Zero Percent Secured Promissory Note | Jack W. Schuler Living Trust              
Operating Loss Carryforwards [Line Items]              
Convertible notes due from related-party extinguished in connection with the exchange transaction, net of deferred issuance costs 34,900            
Secured Debt | August 2022 Exchange Transaction | Five Point Zero Percent Secured Promissory Note | Jack W. Schuler Living Trust              
Operating Loss Carryforwards [Line Items]              
Convertible notes due from related-party extinguished in connection with the exchange transaction, net of deferred issuance costs 49,600            
Capital contribution from related-party in connection with exchange transaction $ 29,800            
Federal              
Operating Loss Carryforwards [Line Items]              
Operating loss carryforwards   383,700          
Operating loss carryforwards, subject to expiration   169,800          
Operating loss carryforwards, not subject to expiration   213,900          
Federal | R&D tax credits              
Operating Loss Carryforwards [Line Items]              
Tax credits   14,500          
State              
Operating Loss Carryforwards [Line Items]              
Operating loss carryforwards   369,600          
State | R&D tax credits              
Operating Loss Carryforwards [Line Items]              
Tax credits   $ 12,400