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ORGANIZATION AND NATURE OF BUSINESS; BASIS OF PRESENTATION; PRINCIPLES OF CONSOLIDATION (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Dec. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Mar. 27, 2018
Organization, Consolidation and Presentation of Financial Statements [Abstract]                        
Accumulated deficit $ (607,239)       $ (570,668)       $ (607,239) $ (570,668)    
Net loss (14,609) $ (15,896) $ (18,523) $ (13,465) (22,803) $ (8,986) $ (21,674) $ (24,239) (62,493) (77,702) $ (78,208)  
Net cash used in operating activities                 (48,728) (47,323) $ (50,394)  
Debt Instrument [Line Items]                        
Cash and cash equivalents and investments $ 45,600       $ 63,600       45,600 $ 63,600    
Decrease in cash and cash equivalents and investments                 $ (18,000)      
2.50% Convertible Notes due 2023 | Convertible Notes                        
Debt Instrument [Line Items]                        
Interest rate                       2.50%